Stimulus-cleavable chemistry in the field of controlled drug delivery

Y Xue, H Bai, B Peng, B Fang, J Baell, L Li… - Chemical Society …, 2021 - pubs.rsc.org
Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …

[HTML][HTML] Recent progress on nanoparticle-based drug delivery systems for cancer therapy

Y Xin, M Yin, L Zhao, F Meng, L Luo - Cancer biology & medicine, 2017 - ncbi.nlm.nih.gov
The development of cancer nanotherapeutics has attracted great interest in the recent
decade. Cancer nanotherapeutics have overcome several limitations of conventional …

Remodelling of the tumour microenvironment by the kallikrein-related peptidases

S Srinivasan, T Kryza, J Batra, J Clements - Nature Reviews Cancer, 2022 - nature.com
Kallikrein-related peptidases (KLKs) are critical regulators of the tumour microenvironment.
KLKs are proteolytic enzymes regulating multiple functions of bioactive molecules including …

The principles and applications of avidin-based nanoparticles in drug delivery and diagnosis

A Jain, K Cheng - Journal of controlled release, 2017 - Elsevier
Avidin-biotin interaction is one of the strongest non-covalent interactions in the nature.
Avidin and its analogues have therefore been extensively utilized as probes and affinity …

Enzyme-responsive polymeric micelles of cabazitaxel for prostate cancer targeted therapy

A Barve, A Jain, H Liu, Z Zhao, K Cheng - Acta biomaterialia, 2020 - Elsevier
Cabazitaxel, a novel tubulin inhibitor with poor affinity for P-glycoprotein, is a second-
generation taxane holding great promise for the treatment of metastatic castration-resistant …

Stimuli-responsive peptide-based biomaterials as drug delivery systems

A Shah, MS Malik, GS Khan, E Nosheen… - Chemical Engineering …, 2018 - Elsevier
Stimuli-responsive proteins have gained a wide spread interest as functional biomaterials in
drug delivery area. However, particular attention has been diverted to peptide-based …

Design of Stimuli‐Responsive Peptides and Proteins

Y Li, G Yang, L Gerstweiler, SH Thang… - Advanced Functional …, 2023 - Wiley Online Library
Stimuli‐responsive peptides and proteins are an exciting class of smart biomaterials for
various applications and have received significant attention over the past decades. A wide …

Surface receptor‐mediated targeted drug delivery systems for enhanced cancer treatment: A state‐of‐the‐art review

S Kunjiappan, P Pavadai, S Vellaichamy… - Drug Development …, 2021 - Wiley Online Library
Enhanced cancer treatment remains as one of the focused areas for researchers around the
world. Hence, the progress in this direction will be a challenge and an opportunity in, inter …

Cell targeting peptides as smart ligands for targeting of therapeutic or diagnostic agents: a systematic review

A Mousavizadeh, A Jabbari, M Akrami… - Colloids and Surfaces B …, 2017 - Elsevier
Cell targeting peptides (CTP) are small peptides which have high affinity and specificity to a
cell or tissue targets. They are typically identified by using phage display and chemical …

Nanocrystal-loaded liposome for targeted delivery of poorly water-soluble antitumor drugs with high drug loading and stability towards efficient cancer therapy

H Liang, F Zou, Q Liu, B Wang, L Fu, X Liang… - International journal of …, 2021 - Elsevier
Nanocrystals (NCs) enable the delivery of poorly water-soluble drugs with improved
dissolution and bioavailability. However, their uncontrolled release and instability make …