Eukaryotic cells engage in autophagy, an internal process of self-degradation through
lysosomes. Autophagy can be classified as selective or non-selective depending on the way …

Autophagy, a catabolic process, degrades damaged and defective cellular materials through
lysosomes, thus working as a recycling mechanism of the cell. It is an evolutionarily …

Pancreatic ductal adenocarcinoma, with the high resistance to chemotherapeutic agents,
remains the fourth leading cause of cancer-death in the world. Due to the wide range of …

Background/Aims: Hepatocellular carcinoma (HCC) is the most common primary liver
malignancy and is a leading cause of cancer-related death worldwide. Luteolin, a flavonoid …

Autophagy is a conserved cellular process required to maintain homeostasis. The hallmark
of autophagy is the formation of a phagophore that engulfs cytosolic materials for …

Cell death is closely related to autophagy under some circumstances; however, the effect of
isoorientin (ISO) on autophagy and the interplay between apoptosis and autophagy in …

Background Emodin, a major component of Polygonum multiflorum (PM), has been reported
to exert both protective and toxic effects in several cell types. However, the effects and …

Effective management of tumorigenesis requires development of better anticancer agents
with greater efficacy and fewer side-effects. Natural products are important sources for the …

Chrysin is a flavonoid found abundantly in substances, such as honey and phytochemicals,
and is known to exhibit anticancer effects against various cancer cells. Nevertheless, the …

Autophagy is an essential catabolic process in mammalian cells to maintain cellular integrity
and viability by degrading the old and damaged cell organelles and other contents with the …