The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity

N Lehnert, E Kim, HT Dong, JB Harland… - Chemical …, 2021 - ACS Publications
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Nitric oxide and the immune response

C Bogdan - Nature immunology, 2001 - nature.com
During the past two decades, nitric oxide (NO) has been recognized as one of the most
versatile players in the immune system. It is involved in the pathogenesis and control of …

[PDF][PDF] Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes

R Karki, BR Sharma, S Tuladhar, EP Williams… - Cell, 2021 - cell.com
COVID-19 is characterized by excessive production of pro-inflammatory cytokines and acute
lung damage associated with patient mortality. While multiple inflammatory cytokines are …

Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer

N Khansari, Y Shakiba… - Recent patents on …, 2009 - ingentaconnect.com
Chronic inflammation is a pathological condition characterized by continued active
inflammation response and tissue destruction. Many of the immune cells including …

Radical causes of cancer

SP Hussain, LJ Hofseth, CC Harris - Nature Reviews Cancer, 2003 - nature.com
Free radicals are ubiquitous in our body and are generated by normal physiological
processes, including aerobic metabolism and inflammatory responses, to eliminate invading …

Mitochondrial regulation of cell cycle and proliferation

VG Antico Arciuch, ME Elguero… - Antioxidants & redox …, 2012 - liebertpub.com
Eukaryotic mitochondria resulted from symbiotic incorporation of α-proteobacteria into
ancient archaea species. During evolution, mitochondria lost most of the prokaryotic …

[HTML][HTML] Current advances of nitric oxide in cancer and anticancer therapeutics

J Mintz, A Vedenko, O Rosete, K Shah, G Goldstein… - Vaccines, 2021 - mdpi.com
Nitric oxide (NO) is a short-lived, ubiquitous signaling molecule that affects numerous critical
functions in the body. There are markedly conflicting findings in the literature regarding the …

The yin and yang of nitric oxide in cancer progression

AJ Burke, FJ Sullivan, FJ Giles, SA Glynn - Carcinogenesis, 2013 - academic.oup.com
Nitric oxide (NO) is a short-lived, pleiotropic molecule that affects numerous critical functions
in the body. Presently, there are markedly conflicting findings in the literature regarding NO …

Propolis and the immune system: a review

JM Sforcin - Journal of ethnopharmacology, 2007 - Elsevier
Propolis has been used empirically for centuries and it was always mentioned as an
immunomodulatory agent. In recent years, in vitro and in vivo assays provided new …

Reprogramming the tumor microenvironment: tumor-induced immunosuppressive factors paralyze T cells

AA Wu, V Drake, HS Huang, SC Chiu, L Zheng - Oncoimmunology, 2015 - Taylor & Francis
It has become evident that tumor-induced immuno-suppressive factors in the tumor
microenvironment play a major role in suppressing normal functions of effector T cells …