G protein–coupled receptor (GPCR) kinases (GRKs) and arrestins interact with agonist-
bound GPCRs to promote receptor desensitization and downregulation. They also trigger …

G-protein coupled receptors (GPCRs) transduce a wide range of extracellular signals. They
are key players in the majority of biologic functions including vision, olfaction, chemotaxis …

Macrophages are immune cells that are widespread throughout the body and critical for
maintaining tissue homeostasis. Their remarkable plasticity allows them to acquire different …

Introduction Strong scientific evidence and large experience support the use of β2-agonists
for the symptomatic alleviation of COPD. Therefore, there is considerable effort in …

Sepsis is defined as a life-threatening dysfunction due to a dysregulated host response to
infection. It is a common and complex syndrome and is the leading cause of death in …

G protein-coupled receptors (GPCRs) are expressed in a variety of cell types and tissues,
and activation of GPCRs is involved in enormous metabolic pathways, including nutrient …

G protein coupled receptors (GPCRs) are a superfamily of transmembrane-spanning
receptors that are activated by multiple endogenous ligands and are the most common …

Актуальность темы. Регуляция функции мышечной оболочки мочеточника (МОМ) при
траффике конкрементов остается малоизученной проблемой патофизиологии. В …