Antimicrobial peptides—Mechanisms of action, antimicrobial effects and clinical applications

J Talapko, T Meštrović, M Juzbašić, M Tomas, S Erić… - Antibiotics, 2022 - mdpi.com
The growing emergence of antimicrobial resistance represents a global problem that not
only influences healthcare systems but also has grave implications for political and …

A review on the research progress on non-pharmacological therapy of Helicobacter pylori

Q Luo, N Liu, S Pu, Z Zhuang, H Gong… - Frontiers in …, 2023 - frontiersin.org
Helicobacter pylori is a pathogenic microorganism that mainly resides in the human stomach
and is the major cause of chronic gastritis, peptic ulcer and gastric cancer. Up to now, the …

Antimicrobial peptides mediate apoptosis by changing mitochondrial membrane permeability

H Wang, C Zhang, M Li, C Liu, J Wang, X Ou… - International Journal of …, 2022 - mdpi.com
Changes in mitochondrial membrane permeability are closely associated with mitochondria-
mediated apoptosis. Antimicrobial peptides (AMPs), which have been found to enter cells to …

Antimicrobial peptides with rigid linkers against gram-negative bacteria by targeting lipopolysaccharide

H Yang, L Wang, L Yuan, H Du, B Pan… - Journal of Agricultural …, 2022 - ACS Publications
A series of hybrid peptides were designed by connecting an antimicrobial peptide Ce (1–8)
with a lipopolysaccharide (LPS)-targeting peptide Lf (28–34) via different linkers …

Anti-Biofilm Effects of Rationally Designed Peptides against Planktonic Cells and Pre-Formed Biofilm of Pseudomonas aeruginosa

YM Kim, H Son, SC Park, JK Lee, MK Jang, JR Lee - Antibiotics, 2023 - mdpi.com
Biofilms are resistant to antibiotics and are a major source of persistent and recurring
infections by clinically important pathogens. Drugs used for biofilm-associated infections are …

Enhancing the Antimicrobial Properties of Peptides through Cell-Penetrating Peptide Conjugation: A Comprehensive Assessment

SV Kravchenko, PA Domnin, SY Grishin… - International Journal of …, 2023 - mdpi.com
Combining antimicrobial peptides (AMPs) with cell-penetrating peptides (CPPs) has shown
promise in boosting antimicrobial potency, especially against Gram-negative bacteria. We …

Antibacterial peptides from Monochamus alternatus induced oxidative stress and reproductive defects in pine wood nematode through the ERK/MAPK signaling …

L Yu, M Yang, D Jiang, H Jin, Z Jin, X Chu… - Pesticide biochemistry …, 2023 - Elsevier
Pine wilt disease is a devastating disease of pine caused by the pine wood nematode
(PWN) Bursaphelenchus xylophilus. Long-term use of chemical nematicides leads to the …

Antibacterial Effect of Sesame Protein-Derived Peptides against Escherichia coli and Staphylococcus aureus: In Silico and In Vitro Analysis

Z Zhu, F Pan, O Wang, L Zhao, L Zhao - Nutrients, 2024 - mdpi.com
This study aimed to screen out antibacterial peptides derived from sesame (Sesamum
indicum L.) through in silico and in vitro methods. In silico proteolysis of sesame proteins …

Molecular Aspects of the Functioning of Pathogenic Bacteria Biofilm Based on Quorum Sensing (QS) Signal-Response System and Innovative Non-Antibiotic …

E Juszczuk-Kubiak - International Journal of Molecular Sciences, 2024 - mdpi.com
One of the key mechanisms enabling bacterial cells to create biofilms and regulate crucial
life functions in a global and highly synchronized way is a bacterial communication system …

Exploring Cyclic Peptide Nanotube Stability Across Diverse Lipid Bilayers and Unveiling Water Transport Dynamics

R Moral, S Paul - Langmuir, 2023 - ACS Publications
Cyclic Peptide Nanotubes (CPNTs) have emerged as compelling candidates for various
applications, particularly as nanochannels within lipid bilayers. In this study, the stability of …