Comparative effectiveness of analgesics to reduce acute pain in the prehospital setting

DM Sobieraj, BK Martinez, B Miao… - Prehospital …, 2020 - Taylor & Francis
Objectives: The objectives of this study were to assess comparative effectiveness and harms
of opioid and nonopioid analgesics for the treatment of moderate to severe acute pain in the …

Use of ketamine for prehospital pain control on the battlefield: a systematic review

G de Rocquigny, C Dubecq, T Martinez… - Journal of Trauma …, 2020 - journals.lww.com
BACKGROUND Intravenous ketamine is commonly used for pain management in the
civilian prehospital setting. Several studies have evaluated its effectiveness in the military …

An analysis of 13 years of prehospital combat casualty care: implications for maintaining a ready medical force

SG Schauer, JF Naylor, AD Fisher… - Prehospital …, 2022 - Taylor & Francis
Background: Most potentially preventable deaths occur in the prehospital setting before
reaching a military treatment facility with surgical capabilities. Thus, optimizing the care we …

Effects of an intravenous ketamine infusion on inflammatory cytokine levels in male and female Sprague–Dawley rats

HF Spencer, RY Berman, M Boese, M Zhang… - Journal of …, 2022 - Springer
Background Ketamine, a multimodal dissociative anesthetic drug, is widely used as an
analgesic following traumatic injury. Although ketamine may produce anti-inflammatory …

Systemic inflammation induced from remote extremity trauma is a critical driver of secondary brain injury

CJ Rowe, J Mang, B Huang, K Dommaraju… - Molecular and Cellular …, 2023 - Elsevier
Blast exposure, commonly experienced by military personnel, can cause devastating life-
threatening polysystem trauma. Despite considerable research efforts, the impact of the …

Trends in prehospital analgesia administration by US forces from 2007 through 2016

SG Schauer, JF Naylor, JK Maddry… - Prehospital …, 2019 - Taylor & Francis
Abstract Background: Tactical Combat Casualty Care (TCCC) guidelines regarding
prehospital analgesia agents have evolved. The guidelines stopped recommending …

Analgesia in pediatric trauma patients in physician-staffed Austrian helicopter rescue: a 12-year registry analysis

C Rugg, S Woyke, J Ausserer, W Voelckel… - Scandinavian journal of …, 2021 - Springer
Background As pediatric patients are typically rare among helicopter emergency medical
systems (HEMS), children might be at risk for oligo-analgesia due to the rescuer's lack of …

Prehospital analgesia for pediatric trauma patients in Iraq and Afghanistan

SG Schauer, AA Arana, JF Naylor, GJ Hill… - Prehospital …, 2018 - Taylor & Francis
Background: Previous studies have evaluated prehospital analgesia during combat
operations in Iraq and Afghanistan, but were limited to the adult population. However, a …

Trends in prehospital blood, crystalloid, and colloid administration in accordance with changes in tactical combat casualty care guidelines

EE Clarke, J Hamm, AD Fisher, MD April… - Military …, 2022 - academic.oup.com
Introduction Hemorrhage is the leading threat to the survival of battlefield casualties. This
study aims to investigate the types of fluids and blood products administered in prehospital …

Effects of a Subanesthetic Ketamine Infusion on Inflammatory and Behavioral Outcomes after Closed Head Injury in Rats

HF Spencer, M Boese, RY Berman, KD Radford… - Bioengineering, 2023 - mdpi.com
Traumatic brain injury (TBI) affects millions of people annually, and most cases are classified
as mild TBI (mTBI). Ketamine is a potent trauma analgesic and anesthetic with anti …