Cyclodextrin-based host–guest supramolecular hydrogels for local drug delivery

G Fang, X Yang, S Chen, Q Wang, A Zhang… - Coordination Chemistry …, 2022 - Elsevier
Cyclodextrin (CD) is one of the most versatile substances produced by nature and can form
supramolecular hydrogels with polymers or small molecules based on non-covalent …

Drug delivery to macrophages: a review of targeting drugs and drug carriers to macrophages for inflammatory diseases

W He, N Kapate, CW Shields IV, S Mitragotri - Advanced drug delivery …, 2020 - Elsevier
Macrophages play a key role in defending against foreign pathogens, healing wounds, and
regulating tissue homeostasis. Driving this versatility is their phenotypic plasticity, which …

[HTML][HTML] An injectable conductive hydrogel restores electrical transmission at myocardial infarct site to preserve cardiac function and enhance repair

L Zhang, T Li, Y Yu, K Shi, Z Bei, Y Qian, Z Qian - Bioactive Materials, 2023 - Elsevier
Myocardial infarction (MI) leads to massive cardiomyocyte death and deposition of collagen
fibers. This fibrous tissue disrupts electrical signaling in the myocardium, leading to cardiac …

Enzyme immobilization in hydrogels: A perfect liaison for efficient and sustainable biocatalysis

J Meyer, LE Meyer, S Kara - Engineering in Life Sciences, 2022 - Wiley Online Library
Biocatalysis is an established chemical synthesis technology that has by no means been
restricted to research laboratories. The use of enzymes for organic synthesis has evolved …

Advances in injectable hydrogel strategies for heart failure treatment

S He, Z Zhang, R Luo, Q Jiang, L Yang… - Advanced Healthcare …, 2023 - Wiley Online Library
Heart failure (HF) affects 60 million people worldwide and has developed into a global
public health problem surpassing cancer and urgently needs to be solved. According to the …

Engineering bioactive synthetic polymers for biomedical applications: A review with emphasis on tissue engineering and controlled release

EJ Bolívar-Monsalve, MM Alvarez, S Hosseini… - Materials …, 2021 - pubs.rsc.org
Synthetic polymers (SyPs) have found many relevant applications niches in biomedical
engineering. Their mechanical properties, defined chemical structure, batch to batch …

[HTML][HTML] An injectable conductive hydrogel with dual responsive release of rosmarinic acid improves cardiac function and promotes repair after myocardial infarction

L Zhang, Z Bei, T Li, Z Qian - Bioactive Materials, 2023 - Elsevier
Myocardial infarction (MI) causes irreversible damage to the heart muscle, seriously
threatening the lives of patients. Injectable hydrogels have attracted extensive attention in …

An injectable peptide hydrogel with excellent self-healing ability to continuously release salvianolic acid B for myocardial infarction

R Chen, C Zhu, L Xu, Y Gu, S Ren, H Bai, Q Zhou… - Biomaterials, 2021 - Elsevier
Drug-loaded hydrogels can improve blood supply and inhibit extracellular matrix
degradation after myocardial infarction. However, due to the continual dynamic motion of …

Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype

JM Bliley, MCSC Vermeer, RM Duffy, I Batalov… - Science translational …, 2021 - science.org
The role that mechanical forces play in shaping the structure and function of the heart is
critical to understanding heart formation and the etiology of disease but is challenging to …

Progress in Stimuli‐Responsive Biomaterials for Treating Cardiovascular and Cerebrovascular Diseases

C Tapeinos, H Gao, T Bauleth‐Ramos, HA Santos - Small, 2022 - Wiley Online Library
Cardiovascular and cerebrovascular diseases (CCVDs) describe abnormal vascular system
conditions affecting the brain and heart. Among these, ischemic heart disease and ischemic …