Hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, also called statins, are
commonly prescribed medications that lower serum cholesterol and decrease cardiac …

This article reviews the evidence for macrophages playing an important role in the
regulation of tumor angiogenesis. Findings in mouse models show that macrophages …

Background Older patients have an average of three comorbidities in addition to their
cancer. Oncologic studies have usually ignored this aspect when adjusting for confounders …

Cohesive scientific evidence from molecular, animal, and human investigations supports the
hypothesis that aberrant induction of COX-2 and up-regulation of the prostaglandin cascade …

AIM: To investigate biological prevention with flavonoids the recurrence risk of neoplasia
was studied in patients with resected colorectal cancer and after adenoma polypectomy …

Colorectal cancer (CRC) is characterized by the partial suppression of apoptosis, which in
turn gives tumours a selective advantage for survival and can cause current chemotherapy …

Colorectal cancer (CRC) is one of the deadliest forms of cancer worldwide. CRC
development occurs mainly through the adenoma-carcinoma sequence, which can last …

Colorectal cancer arises as a result of the accumulation of genetic errors many of which
affect the control of apoptosis. Effective chemoprevention strategies for colorectal cancer …

There is still insufficient data about the risk-benefit profile about recommending non-aspirin,
non-steroidal anti-inflammatory drugs (NA-NSAIDs) for colorectal cancer (CRC) prevention …

Background Studying the differential impact of aspirin and other nonsteroidal anti‐
inflammatory drugs across the stages of colorectal neoplasia from early adenoma to cancer …