Prostate cancer is the most common malignancy among men in Western nations. Previous
studies indicate that non-steroidal anti-inflammatory drugs have an inhibitory effect on …

Abstract Purpose: Cyclooxygenase-2 (COX-2) expression in human colorectal cancer and
adenoma tissue seems to be higher than in normal mucosa. However, data about the …

Objectives. Many elderly patients are prescribed both low-dose aspirin (ASA), for
cardiovascular protection and non-steroidal anti-inflammatory drugs (NSAIDs) for pain …

The present study was carried out to develop and evaluate guar gum-based matrix tablets of
rofecoxib for their intended use in the chemoprevention of colorectal cancer. Matrix tablets …

Gastrin is the main hormone responsible for the stimulation of gastric acid secretion; in
addition, gastrin and its derivatives exert proliferative and antiapoptotic effects on several …

Background. This study compared comorbidity‐related medical care cost associated with
different types of cancer, by examining breast (N= 287), colon (N= 272), stomach (N= 614) …

The present study is an attempt to synthesize nanosized guar gum carriers encapsulating
celecoxib as the chemopreventive agent for experimental colorectal cancer (CRC). Guar …

It has been shown that combination of imatinib (IM) with other agents may have some
advantages in avoiding toxicity and resistance caused by this drug. The selective …

In the third millennium preventive medicine is becoming a corner stone in our concept of
health. Colorectal cancer (CRC) prevention, in particular, has become an important goal for …

Background In-vitro and animal experiments have shown that the cyclo-oxygenase 2
inhibitor celecoxib can reduce formation of neointima within stents. We aimed to test whether …