Effects of Cyclooxygenase-2 Inhibitors on Gastrointestinal Malignancies: a Systematic Review and Meta-analysis

YX Jiang, Y Chen, H Sun, S Xu - Indian Journal of Surgical Oncology, 2022 - Springer
Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) are associated with a reduced
risk of gastrointestinal malignancies, which is thought to be mediated mainly through the …

Colorectal cancer: Epidemiology, etiology, and molecular basis

HG Moore, NN Baxter, JG Guillem - The ASCRS Textbook of Colon and …, 2011 - Springer
Colorectal cancer (CRC) is a disease with a major worldwide burden. It is the fourth most
frequently diagnosed malignancy in men and third most common in women, with almost one …

Ibuprofen in the prevention and therapy of cancer

RE Harris - Ibuprofen: Discovery, Development and …, 2015 - Wiley Online Library
This chapter provides compelling evidence that regular intake of inexpensive and readily
available non‐steroidal anti‐inflammatory drugs (NSAIDs), such as ibuprofen and aspirin …

塞莱西布对甲基硝基亚硝基胍诱导大鼠胃癌的化学预防作用

靖大道, 楼俪泓, 李恩灵, 李继坤 - 中华肿瘤防治杂志, 2007 - cqvip.com
目的: 探讨选择性环氧合酶-2 (COX-2) 抑制剂塞莱西布对N-甲基-N′-硝基-M 亚硝基胍(MNNG)
诱发大鼠胃癌的化学预防作用. 方法: 将120 只雄性Wistar 大鼠分成5 组分别予以不同饮食及 …

大肠癌与细胞凋亡及诱导凋亡治疗

彭远飞, 郑民华 - 上海交通大学学报: 医学版, 2007 - cqvip.com
大肠癌与细胞凋亡及诱导凋亡治疗-[维普官方网站]-www.cqvip.com-维普网  我的维普 购物车
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环氧化酶-2 抑制剂抗肿瘤作用研究现状

马绍英, 王仲文, 赵福林 - 肿瘤研究与临床, 2004 - cqvip.com
环氧化酶-2抑制剂抗肿瘤作用研究现状-[维普官方网站]-www.cqvip.com-维普网  我的维普 购物车
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A potential concept in the management of tumors with modulation of prostaglandin, nitric oxide and antioxidants

NS Al-Waili - The Scientific World Journal, 2007 - Wiley Online Library
Prostaglandins (PGs), nitric oxide (NO), free radicals and chronic inflammation play a major
role in tumorogenesis. We have found in vivo that PGs suppress antibody production; …

Creation of anti-inflammatory pharmaceutical compositions

G Syrova, V Petyunina, V Makarov, L Lukіаnova… - 2022 - repo.knmu.edu.ua
The review article summarizes the data of literature and our own research on the creation of
more effective and safe domestic combined drugs with a pronounced anti-inflammatory and …

Colorectal cancer prevention

A Ismail, E Gerner, P Lance - Fundamentals of Cancer Prevention, 2005 - Springer
CRCs evolve through distinct genetic pathways involving genetic instability, which is the
driving force for tumor development (Lengauer, Kinzler et al. 1998). Three genetic instability …

Cyclooxygenase-2 expression correlates with membrane-type-1 matrix metalloproteinase expression in colorectal cancer tissue

H Guo, A Tatsuguchi, S Shinji, S Fujimori… - Diseases of the colon …, 2006 - journals.lww.com
Purpose: Elevated expression of cyclooxygenase-2 has been found in colorectal cancer.
One of the mechanisms through which cyclooxygenase-2 affects tumorigenesis is through its …