Personal experience, learned eating behaviors, hormones, neurotransmitters, and genetic
variations affect food consumption. The decision of what to eat is modulated by taste …

Sweet substances are detected by taste-bud cells upon binding to the sweet-taste receptor,
a T1R2/T1R3 heterodimeric G protein-coupled receptor. In addition, experiments with …

The human T1R taste receptors are family CG‐protein‐coupled receptors (GPCRs) that act
as heterodimers to mediate sweet (hT1R2+ hT1R3) and umami (hT1R1+ hT1R3) taste …

Taste GPCRs are expressed in taste buds on the tongue and play a key role in food choice
and consumption. They are also expressed extra-orally, with various physiological roles that …

The study of taste has been guided throughout much of its history by the conceptual
framework of psychophysics, where the focus was on quantification of the subjective …

Gustducin, a Gα subunit expressed in taste cells, is known as a key molecule for sweet,
umami and bitter taste signal transduction. However, previous studies demonstrated that the …

Taste receptors for sweet, bitter and umami tastants are G-protein coupled receptors
(GPCRs). While much effort has been devoted to understanding G-protein-receptor …

In order to investigate the molecular mechanism of calcium signaling pathways common to
the vertebrate gustatory systems, we have analyzed the expression of their molecular …

Taste buds are constituted of several kinds of cells which have distinct characteristics and
play different roles. In this study, we have established an in vitro culture system by optimizing …