Role of Fc core fucosylation in the effector function of IgG1 antibodies

J Golay, AE Andrea, I Cattaneo - Frontiers in Immunology, 2022 - frontiersin.org
The presence of fucose on IgG1 Asn-297 N-linked glycan is the modification of the human
IgG1 Fc structure with the most significant impact on FcɣRIII affinity. It also significantly …

N-linked glycans: An underappreciated key determinant of T cell development, activation, and function

M Abdelbary, JC Nolz - Immunometabolism, 2023 - journals.lww.com
N-linked glycosylation is a post-translational modification that results in the decoration of
newly synthesized proteins with diverse types of oligosaccharides that originate from the …

Prenatal opioid-exposed infant extracellular miRNA signature obtained at birth predicts severity of neonatal opioid withdrawal syndrome

AH Mahnke, MH Roberts, L Leeman, X Ma… - Scientific reports, 2022 - nature.com
Prenatal opioid exposure (POE) is commonly associated with neonatal opioid withdrawal
syndrome (NOWS), which is characterized by a broad variability in symptoms and severity …

An integrated mass spectrometry-based glycomics-driven glycoproteomics analytical platform to functionally characterize glycosylation inhibitors

MRS Alvarez, Q Zhou, SJB Grijaldo, CB Lebrilla… - Molecules, 2022 - mdpi.com
Cancer progression is linked to aberrant protein glycosylation due to the overexpression of
several glycosylation enzymes. These enzymes are underexploited as potential anticancer …

Wild and captive environments drive the convergence of gut microbiota and impact health in threatened equids

Z Zhou, L Tang, L Yan, H Jia, Y Xiong… - Frontiers in …, 2022 - frontiersin.org
To explore how the living environment influences the establishment of gut microbiota in
different species, as well as the extent to which changes in the living environment caused by …

Recent Chemical and Chemoenzymatic Strategies to Complex-Type N-Glycans

X Zhao, Y Huang, S Zhou, J Ao, H Cai… - Frontiers in …, 2022 - frontiersin.org
Glycosylation is one of the major forms of protein post-translational modification. N-glycans
attached to proteins by covalent bonds play an indispensable role in intercellular interaction …

NLRP3 Inflammasome-dependent Pathway is Involved in the Pathogenesis of Polycystic Ovary Syndrome

B Wang, M Shi, C Yu, H Pan, H Shen, Y Du… - Reproductive …, 2024 - Springer
Accumulating evidence has shown that inflammation is a key process in polycystic ovary
syndrome (PCOS). Nucleotide-binding oligomerization domain-, leucine-rich repeat-, and …

Direct Glycan Analysis of Biological Samples and Intact Glycoproteins by Integrating Machine Learning-Driven Surface-Enhanced Raman Scattering and Boronic Acid …

Q Hu, HJ Wu - ACS Measurement Science Au, 2024 - ACS Publications
Frequent monitoring of glycan patterns is a critical step in studying glycan-mediated cellular
processes. However, the current glycan analysis tools are resource-intensive and less …

Identifying genes involved in the secretory physiological response to feeding in Pacific White Shrimp (Litopenaeus vannamei) using transcriptomics

H Chen, Z Li, H Yang, J Zhang, A Farhadi… - … and Physiology Part A …, 2024 - Elsevier
The physiological response to feeding is important for production aspects that include feed
utilization and growth, and the responses require the action of numerous secretory factors …

Characteristics of phosgene aspiration lung injury analyzed based on transcriptomics and proteomics

LN Wang, YR Shao, PF Wang, J Lv, DK He - Frontiers in Genetics, 2024 - frontiersin.org
Background Phosgene is a chemical material widely used worldwide. No effective method
has been developed to reverse its pathological injuries. Some studies have shown that …