Radiolabelling of nanomaterials for medical imaging and therapy

J Pellico, PJ Gawne, RTM de Rosales - Chemical Society Reviews, 2021 - pubs.rsc.org
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases

D Furtado, M Björnmalm, S Ayton, AI Bush… - Advanced …, 2018 - Wiley Online Library
Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …

The efficiency of metal, metal oxide, and metalloid nanoparticles against cancer cells and bacterial pathogens: different mechanisms of action

M Alavi, M Rai, F Martinez, D Kahrizi… - Cellular, Molecular …, 2022 - cmbr-journal.com
The applications of nanoparticles in various practical fields, owing to their unique properties
compared with bulk materials, have been occupying the minds of scientists for several …

Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

S Mitragotri, PA Burke, R Langer - Nature reviews Drug discovery, 2014 - nature.com
The formulation and delivery of biopharmaceutical drugs, such as monoclonal antibodies
and recombinant proteins, poses substantial challenges owing to their large size and …

Physicochemical characteristics of nanoparticles affect circulation, biodistribution, cellular internalization, and trafficking

X Duan, Y Li - Small, 2013 - Wiley Online Library
Nanoparticles have many potential applications in tumor therapy. Systemically administered
nanoparticles should remain in circulation for a long time to increase their accumulation in …

Polymeric membranes for biomedical applications

ER Radu, SI Voicu, VK Thakur - Polymers, 2023 - mdpi.com
Polymeric membranes are selective materials used in a wide range of applications that
require separation processes, from water filtration and purification to industrial separations …

Drug delivery system based on pH-sensitive biocompatible poly (2-vinyl pyridine)-b-poly (ethylene oxide) nanomicelles loaded with curcumin and 5-fluorouracil

CE Iurciuc-Tincu, MS Cretan, V Purcar, M Popa… - Polymers, 2020 - mdpi.com
Smart polymeric micelles (PMs) are of practical interest as nanocarriers for the
encapsulation and controlled release of hydrophobic drugs. Two hydrophobic drugs …

Technetium‐99m radiochemistry for pharmaceutical applications

D Papagiannopoulou - Journal of Labelled Compounds and …, 2017 - Wiley Online Library
Technetium‐99m (99mTc) is a widely used radionuclide, and the development of 99mTc
imaging agents continues to be in demand. This overview discusses basic principles of …

[HTML][HTML] Nonordered dendritic mesoporous silica nanoparticles as promising platforms for advanced methods of diagnosis and therapies

S Malekmohammadi, RUR Mohammed… - Materials Today …, 2022 - Elsevier
Dendritic mesoporous silica nanoparticles (DMSNs) are a new generation of porous
materials that have gained great attention compared to other mesoporous silicas due to …

Bone metastasis targeting: a novel approach to reach bone using Zoledronate anchored PLGA nanoparticle as carrier system loaded with Docetaxel

KR Chaudhari, A Kumar, VKM Khandelwal… - Journal of controlled …, 2012 - Elsevier
In spite of good research in drug delivery, bone targeting remains largely unexplored. Even
some of the bone diseases are seldom cured just because of poor distribution of drug at the …