Domestic animal models for biomedical research

A Bähr, E Wolf - Reproduction in domestic animals, 2012 - Wiley Online Library
Contents Experimental animals in biomedical research provide insights into disease
mechanisms and models for determining the efficacy and safety of new therapies and for …

[HTML][HTML] Sex and breed-dependent organ development and metabolic responses in foetuses from lean and obese/leptin resistant swine

L Torres-Rovira, A Tarrade, S Astiz, E Mourier… - PloS one, 2013 - journals.plos.org
The present study aimed to determine the effects of breed and sex on growth patterns and
metabolic features of advanced-pregnancy foetuses exposed to the same environmental …

Mutations in the leptin receptor gene associated with delayed onset of puberty are also associated with decreased ovulation and lambing rates in prolific Davisdale …

JL Juengel, MC French, AR O'Connell… - Reproduction …, 2016 - CSIRO Publishing
The aim of this study was to determine if single nucleotide polymorphisms (SNPs) in the
leptin receptor (LEPR) gene associated with delayed onset of puberty are associated with …

Reproductive, endocrine and metabolic feto-maternal features and placental gene expression in a swine breed with obesity/leptin resistance

A Gonzalez-Bulnes, L Torres-Rovira, C Ovilo… - General and …, 2012 - Elsevier
The current study was conducted in a swine breed (Iberian pig) with a genotype that
predisposed the pig to obesity. The aim of the study was to determine the morphological …

Maternal high-fat diet induces follicular atresia but does not affect fertility in adult rabbit offspring

P Léveillé, A Tarrade, C Dupont, T Larcher… - … origins of health and …, 2014 - cambridge.org
Alterations to the metabolic environment in utero can have an impact on subsequent female
reproductive performance. Here, we used a model of rabbits receiving a high-fat diet (H diet; …

The interaction between ovulation rate and embryo survival in determining prolificacy of different strains of obese swine with gene polymorphisms for leptin receptors

L Torres-Rovira, P Gonzalez-Añover… - Animal Production …, 2011 - CSIRO Publishing
The Mediterranean Iberian pigs show a clear predisposition to obesity, due to gene
polymorphisms for leptin receptors, and a lower prolificacy when compared with lean …

Efectos postnatales de la variación de peso al nacimiento en el cerdo ibérico

M Vázquez Gómez - 2019 - docta.ucm.es
The increasing demand for high-quality dry-cured products from fatty breeds has changed
management practices into more intensive rearing as in lean breeds. The current …

Effects of Lifestyle on Female Reproductive Features and Success: Lessons from Animal Models

A Gonzalez-Bulnes, S Astiz - Handbook of Fertility, 2015 - Elsevier
There is increasing epidemiological evidence that nonoptimal diet and lifestyle affect
reproduction; the current availability of high-energy diet and the sedentary habits of modern …

[HTML][HTML] Efectos postnatales de la variación de peso al nacimiento en el cerdo ibérico

MV Gómez - 2018 - dialnet.unirioja.es
La optimización de la rentabilidad en el sector porcino se basa en el aumento de los kilos
de carne obtenidos por cerda y en conseguir una mayor homogeneidad en los lotes …

Developmental competence of antral follicles and their oocytes after gonadotrophin treatment of sows with gene polymorphisms for leptin and melanocortin receptors …

J Muñoz-Frutos, T Encinas, P Pallares… - Journal of assisted …, 2011 - Springer
Purpose To evaluate possible differences in follicle and oocyte developmental competence
after gonadotrophin treatment in sows of obese and lean genotypes. Methods Follicle …