Biofilms: formation, research models, potential targets, and methods for prevention and treatment

Y Su, JT Yrastorza, M Matis, J Cusick, S Zhao… - Advanced …, 2022 - Wiley Online Library
Due to the continuous rise in biofilm‐related infections, biofilms seriously threaten human
health. The formation of biofilms makes conventional antibiotics ineffective and dampens …

[HTML][HTML] The potential of human peptide LL-37 as an antimicrobial and anti-biofilm agent

KE Ridyard, J Overhage - Antibiotics, 2021 - mdpi.com
The rise in antimicrobial resistant bacteria threatens the current methods utilized to treat
bacterial infections. The development of novel therapeutic agents is crucial in avoiding a …

Dissolvable Microneedles Coupled with Nanofiber Dressings Eradicate Biofilms via Effectively Delivering a Database-Designed Antimicrobial Peptide

Y Su, VL Mainardi, H Wang, A McCarthy, YS Zhang… - ACS …, 2020 - ACS Publications
Biofilms in chronic wounds, including diabetic foot ulcers, pressure ulcers, and venous leg
ulcers, pose a major challenge to wound management. Herein, we report a Janus-type …

Design of antimicrobial peptides: progress made with human cathelicidin LL-37

G Wang, JL Narayana, B Mishra, Y Zhang… - … Peptides: Basics for …, 2019 - Springer
The incorporation of the innate immune system into humans is essential for survival and
health due to the rapid replication of invading microbes and the delayed action of the …

Antimicrobial peptides: An alternative to traditional antibiotics

S Ji, F An, T Zhang, M Lou, J Guo, K Liu, Y Zhu… - European Journal of …, 2023 - Elsevier
As antibiotic-resistant bacteria and genes continue to emerge, the identification of effective
alternatives to traditional antibiotics has become a pressing issue. Antimicrobial peptides …

[HTML][HTML] Antibiofilm and anti-quorum sensing potential of cycloartane-type triterpene acids from Cameroonian grassland propolis: phenolic profile and antioxidant …

AN Tamfu, O Ceylan, G Cârâc, E Talla, RM Dinica - Molecules, 2022 - mdpi.com
Propolis is very popular for its beneficial health properties, such as antimicrobial activity and
antioxidant effects. It is one of the most long-serving traditional medicines to mankind due to …

[HTML][HTML] Inhibition and Eradication of Pseudomonas aeruginosa Biofilms by Host Defence Peptides

H Chen, RW Wubbolts, HP Haagsman… - Scientific reports, 2018 - nature.com
P. aeruginosa is a notorious biofilm producer that causes a wide variety of acute and chronic
infections. In this study the in vitro anti-biofilm activity of 13 Host Defence Peptides from …

[HTML][HTML] A stable cyclized antimicrobial peptide derived from LL-37 with host immunomodulatory effects and activity against uropathogens

JK White, T Muhammad, E Alsheim, S Mohanty… - Cellular and Molecular …, 2022 - Springer
The increasing antibiotic resistance among uropathogenic bacteria warrants alternative
therapeutic strategies. We demonstrate the potential of the synthetic peptide CD4-PP …

In vitro and in vivo antimicrobial activity of antimicrobial peptide Jelleine-I against foodborne pathogen Listeria monocytogenes

P Shen, K Ding, L Wang, J Tian, X Huang… - International Journal of …, 2023 - Elsevier
As a human foodborne pathogen, Listeria monocytogenes can cause severe human
listeriosis and develop resistance to antibiotics. Antimicrobial peptides (AMPs) are produced …

Transparent silk fibroin film-facilitated infected-wound healing through antibacterial, improved fibroblast adhesion and immune modulation

J Zhang, L Wang, C Xu, Y Cao, S Liu… - Journal of Materials …, 2024 - pubs.rsc.org
The clinical application of regenerated silk fibroin (RSF) films for wound treatment is
restricted by its undesirable mechanical properties and lack of antibacterial activity. Herein …