Role of inflammatory mechanisms in major depressive disorder: from etiology to potential pharmacological targets

BR Kouba, L de Araujo Borba, P Borges de Souza… - Cells, 2024 - mdpi.com
The involvement of central and peripheral inflammation in the pathogenesis and prognosis
of major depressive disorder (MDD) has been demonstrated. The increase of pro …

[HTML][HTML] Immune-mediated diseases from the point of view of psychoneuroimmunoendocrinology

MA Ortega, C García-Montero, O Fraile-Martinez… - Biology, 2022 - mdpi.com
Simple Summary Immune-mediated inflammatory diseases (IMIDs) are growing in
prevalence and relevance in our society, entailing notable consequences for the individual …

Antidepressant effects of a polysaccharide from okra (Abelmoschus esculentus (L) Moench) by anti-inflammation and rebalancing the gut microbiota

T Yan, T Nian, Z Liao, F Xiao, B Wu, K Bi, B He… - International journal of …, 2020 - Elsevier
The present study aimed to evaluate the antidepressant-like effect of a polysaccharide (OP),
which is isolated from okra (Abelmoschus esculentus (L) Moench), in CUMS-induced mice …

Choroid plexus volume is increased in mood disorders and associates with circulating inflammatory cytokines

B Bravi, EMT Melloni, M Paolini, M Palladini… - Brain, Behavior, and …, 2024 - Elsevier
Depressed patients exhibit altered levels of immune-inflammatory markers both in the
peripheral blood and in the cerebrospinal fluid (CSF) and inflammatory processes have …

Increased inflammation predicts nine-year change in major depressive disorder diagnostic status.

NH Zainal, MG Newman - Journal of abnormal psychology, 2021 - psycnet.apa.org
Cytokine theory of depression proposes that increased baseline inflammatory activity may
accumulate over time and lead to future major depressive disorder (MDD). However, most …

Pioglitazone metformin complex improves polycystic ovary syndrome comorbid psychological distress via inhibiting NLRP3 inflammasome activation: a prospective …

Q Guo, J Shan, Y Xu, Y Hu, C Huo… - Mediators of …, 2020 - Wiley Online Library
Objective. This study aimed at investigating the therapeutic effect and mechanism of
pioglitazone metformin complex preparation (PM) in polycystic ovary syndrome (PCOS) …

Evaluation of DNA methylation in BDNF, SLC6A4, NR3C1 and FKBP5 before and after treatment with selective serotonin-reuptake inhibitor in major depressive …

S Mohammadi, A Beh-Pajooh, M Ahmadimanesh… - …, 2022 - Taylor & Francis
Aim: To identify the DNA methylation status of related genes in major depressive disorder
following selective serotonin-reuptake inhibitor treatment. Materials & methods: 45 patients …

[HTML][HTML] Optimizing and predicting antidepressant efficacy in patients with major depressive disorder using multi-omics analysis and the Opade AI prediction tools

G Corrivetti, F Monaco, A Vignapiano, A Marenna… - Brain Sciences, 2024 - mdpi.com
According to the World Health Organization (WHO), major depressive disorder (MDD) is the
fourth leading cause of disability worldwide and the second most common disease after …

[HTML][HTML] Myocarditis and coronavirus disease 2019 vaccination: A systematic review and meta-summary of cases

PBT Saputra, RB Kurniawan, D Trilistyoati… - Biomolecules and …, 2023 - ncbi.nlm.nih.gov
Vaccination is significant to control, mitigate, and recover from the destructive effects of
coronavirus disease 2019 (COVID-19). The incidence of myocarditis following COVID-19 …

[HTML][HTML] The association of FKBP5 gene polymorphism with genetic susceptibility to depression and response to antidepressant treatment-a systematic review

Y Zhang, W Yue, J Li - BMC psychiatry, 2024 - Springer
Background Given the inconsistencies in current studies regarding the impact of FKBP5
gene polymorphisms on depression, arising from variations in study methods, subjects, and …