The goals of the subcommittee were to review the current practice and published evidence
of medical and surgical treatment options for meibomian gland dysfunction (MGD) and to …

Dry eye disease (DED) is a common, multifactorial ocular condition with major impact on
vision and quality of life. It is now well recognized that the pathophysiology of chronic DED …

There are many proposed non-antimicrobial actions of tetracyclines. Pathways affected by
these medications are often overexpressed in various dermatologic conditions. Matrix …

Background Dry eye disease (DED) is among the most prevalent ophthalmic conditions but
is often underdiagnosed and mistreated. Antibiotics are regularly used to treat DED caused …

PURPOSE: To describe the cause and consequence of tear dysfunction–related corneal
disease. DESIGN: Perspective on effects of tear dysfunction on the cornea. METHODS …

Purpose: To evaluate the importance and practicality of testing for matrix metalloproteinase
9 (MMP-9) in dry eye and ocular surface disease. This enzyme, which can cause tissue …

The objective of this research was to determine the effect of oral minocycline on the
meibomian gland nonpolar and free fatty acid lipids of chronic blepharitis patients. Patients …

Dry eye is a common ocular surface disease of multifactorial etiology characterized by
elevated tear osmolality and inflammation leading to a disrupted ocular surface. The latter is …

Purpose.: We investigated the therapeutic effects and underlying mechanisms of topical
doxycycline in a benzalkonium chloride (BAC)–induced mouse dry eye model. Methods …

Blepharitis is a condition characterized by inflammation of the eyelid margin and is a
common cause of discomfort and irritation among people of all ages, ethnicity, and sex. In …