In recognition of the importance of zebrafish as a model organism for studying human
disease, we have created zebrafish content for a web-based reference atlas of …

Diamond-Blackfan anemia (DBA) is a rare congenital erythroblastopenia and inherited bone
marrow failure syndrome that affects approximately seven individuals in every million live …

Protein synthesis on ribosomes is carefully quality-controlled to ensure the faithful
transmission of genetic information from mRNA to protein. Many of these mechanisms rely …

Truncation of the tumour suppressor adenomatous polyposis coli (APC) constitutively
activates the Wnt/β‐catenin signalling pathway. This event constitutes the primary …

Ductal carcinoma in situ (DCIS) is considered a non-invasive precursor to breast cancer,
and although associated with an increased risk of developing invasive disease, many …

A major goal of cancer research has been to identify genes that contribute to cancer
formation. The similar pathology between zebrafish and human tumors, as well as the past …

Ribosome biogenesis and protein synthesis are two of the most energy consuming
processes in a growing cell. Moreover, defects in their molecular components can alter the …

Ribosome is responsible for protein synthesis in all organisms and ribosomal proteins (RPs)
play important roles in the formation of a functional ribosome. L11 was recently shown to …

Several somatic ribosome defects have recently been discovered in cancer, yet their
oncogenic mechanisms remain poorly understood. Here we investigated the pathogenic …

Bmyb is a ubiquitously expressed transcription factor involved in cellular proliferation and
cancer,,,. Loss of bmyb function in the zebrafish mutant crash&burn (crb) results in …