Dimethylarsinic acid (DMA) is a major metabolite in the urine of humans and rats exposed to
inorganic arsenicals, and is reported to induce rat bladder carcinogenesis. In the present …

The purpose of present study was to characterize the endoplasmic reticulum stress and
generation of ROS in rat liver RLC-16 cells by exposing to trivalent dimethylarsinous acid …

Arsenic speciation in blood can improve understanding of the metabolism and toxicity of
arsenic. In this study, arsenic species in the plasma and red blood cells (RBCs) of arsenite …

Arsenic in hair and nails has been used to assess chronic exposure of humans to
environmental arsenic. However, it remains to be seen whether it is appropriate to evaluate …

In safety evaluations of chemicals, there is an urgent need to develop short-term methods to
replace long-term carcinogenicity tests. We have reported that immunohistochemistry for γ …

We synthesised and toxicologically characterised the arsenic metabolite thiodimethylarsinic
acid (thio‐DMAV). Successful synthesis of highly pure thio‐DMAV was confirmed by state‐of …

Although inorganic arsenic has long been recognized as a potent toxicant and carcinogen in
humans, recent evidence shows that at least some of its effects are mediated by methylated …

Susceptibility to the toxic effects of arsenic is influenced by an organism's capacity for
arsenic metabolism. To fully understand this potential, the pathways and properties of …

Arsenic (As) is a colorless and tasteless naturally occurring metalloid found in water, air and
soil. There are two forms of As, ie, inorganic and organic, the former form is of serious health …

Inorganic arsenic (iA) in the drinking water is a human carcinogen (bladder, lung, and skin).
The mode of action involves metabolism to trivalent arsenicals that react with sulfhydryl …