[HTML][HTML] Loss of heterozygosity in the tumor DNA of De Novo diagnosed patients is associated with poor outcome for B-ALL but Not for T-ALL

N Risinskaya, Y Kozhevnikova, O Gavrilina… - Genes, 2022 - mdpi.com
Despite the introduction of new technologies in molecular diagnostics, one should not
underestimate the traditional routine methods for studying tumor DNA. Here we present the …

[HTML][HTML] Integrated genomic analysis of chromosomal alterations and mutations in B-cell acute lymphoblastic leukemia reveals distinct genetic profiles at relapse

M Forero-Castro, A Montaño, C Robledo… - Diagnostics, 2020 - mdpi.com
The clonal basis of relapse in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is
complex and not fully understood. Next-generation sequencing (NGS), array comparative …

[HTML][HTML] Intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia: study of 3 cases

A Mroczkowska, M Lejman - Case Reports in Oncology, 2021 - karger.com
Acute lymphoblastic leukemia (ALL) is the most common malignancy of childhood. The
presence or absence of a characteristic genetic abnormality usually observed in childhood …

[HTML][HTML] Molecular Genomics in Precision Hematopathology

X Li, KT Schafernak - Hematopathology, 2022 - journals.librarypublishing.arizona …
This section focuses on the molecular tools employed in precision hematopathology. Dr. Xia
Li in a her presentation led us through anew journey to genomics and precision medicine by …

[引用][C] Myeloperoxidase‐positive bilineal mixed phenotype acute leukemia (B/T) with chromosome copy neutral loss of heterozygosity exhibits simultaneous diffuse …

K Huang, Y Du, M Wu, Y Li, D Nie… - Pediatric Blood & …, 2023 - Wiley Online Library
To the Editor: A 28-year-old female was admitted with multiple arthralgias. Complete blood
count revealed: white blood cell 4.57× 109/L, hemoglobin 96 g/L, platelet 75× 109/L …