The RNA-binding proteins (RBPs) are critical trans factors that associate with specific cis
elements present in mRNAs whose stability and translation are subject to regulation. The …

Altered gene expression is a characteristic feature of many disease states such as
tumorigenesis, and in most cancers, it facilitates cancer cell survival and adaptation …

The control of eukaryotic gene expression occurs at multiple levels, from transcription to
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …

The compelling need to provide adoptive cell therapy (ACT) to an increasing number of
oncology patients within a meaningful therapeutic window makes the development of an …

The majority of the genome is transcribed into pieces of non-(protein) coding RNA, among
which long non-coding RNAs (lncRNAs) constitute a large group of particularly versatile …

Metastasis is the main cause of mortality in renal cell carcinoma (RCC). Circular RNAs
(circRNAs) involvement in RCC metastasis has been described, although the underlying …

Glucose is a universal bioenergy source; however, its role in controlling protein interactions
is unappreciated, as are its actions during differentiation-associated intracellular glucose …

Nuclear clearance of the RNA-binding protein TDP-43 is a hallmark of neurodegeneration
and an important therapeutic target. Our current understanding of TDP-43 …

The obesity epidemic represents a critical public health issue worldwide, as it is a vital risk
factor for many diseases, including type 2 diabetes (T2D) and cardiovascular disease …

Circular RNAs (circRNAs) are critical regulators in the occurrence and development of
numerous cancers, in which abnormal autophagy plays a key role. However, the potential …