Genetic information that is transcribed from DNA to mRNA, and then translated from mRNA
to protein, is regulated by complex and sophisticated post-transcriptional mechanisms …

Recognition of single-stranded RNA (ssRNA) by RNA recognition motif (RRM) domains is
an important class of protein–RNA interactions. Many such complexes were characterized …

Insulin-like growth factor 2 mRNA-binding proteins (IMPs, IGF2BPs) act in mRNA transport
and translational control but are oncofetal tumor marker proteins. The IMP protein family …

Nearly 7.5% of all human protein-coding genes have been assigned to the class of RNA-
binding proteins (RBPs), and over the past decade, RBPs have been increasingly …

Abstract Sirtuin-1 (SIRT1) as a NAD+-dependent Class III protein deacetylase, involves in
longevity and various cellular physiological processes. SIRT1 via deacetylating transcription …

Abstract The Human antigen R (HuR) protein is an RNA-binding protein, ubiquitously
expressed in human tissues, that orchestrates target RNA maturation and processing both in …

Glioblastoma (GBM) is a malignant and aggressive brain tumor with a median survival of∼
15 months. Resistance to treatment arises from the extensive cellular and molecular …

RNA-binding proteins (RBPs) are involved in regulating all aspects of RNA metabolism,
including processing, transport, translation, and degradation. Dysregulation of RNA …

The RNA-binding protein human antigen R (HuR) is a well-established regulator of gene
expression at the posttranscriptional level. Its dysregulation has been implicated in various …

Embryonic development requires tight control of gene expression levels, activity, and
localisation. This control is coordinated by multiple levels of regulation on DNA, RNA and …