[HTML][HTML] Epigenetic changes in the pathogenesis of rheumatoid arthritis

MV Nemtsova, DV Zaletaev, IV Bure… - Frontiers in …, 2019 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects about 1% of the
world's population. The etiology of RA remains unknown. It is considered to occur in the …

Dysregulation of microRNAs in autoimmune diseases: Pathogenesis, biomarkers and potential therapeutic targets

H Long, X Wang, Y Chen, L Wang, M Zhao, Q Lu - Cancer letters, 2018 - Elsevier
MicroRNAs (miRNAs) are small, single-stranded, endogenous non-coding RNAs that
repress the expression of target genes via post-transcriptional mechanisms. Due to their …

[HTML][HTML] Transformation of fibroblast‐like synoviocytes in rheumatoid arthritis; from a friend to foe

MJ Mousavi, J Karami, S Aslani, MN Tahmasebi… - Autoimmunity …, 2021 - Springer
Swelling and the progressive destruction of articular cartilage are major characteristics of
rheumatoid arthritis (RA), a systemic autoimmune disease that directly affects the synovial …

[HTML][HTML] Cytokine targeting by miRNAs in autoimmune diseases

V Salvi, V Gianello, L Tiberio, S Sozzani… - Frontiers in …, 2019 - frontiersin.org
Persistent and excessive cytokine production is a hallmark of autoimmune diseases and
may play a role in disease pathogenesis and amplification. Therefore, cytokine …

Clinical significance of miRNAs in autoimmunity

L Zhang, H Wu, M Zhao, C Chang, Q Lu - Journal of autoimmunity, 2020 - Elsevier
MicroRNAs (miRNAs) are evolutionally conserved, single-stranded RNAs that regulate gene
expression at the posttranscriptional level by disrupting translation. MiRNAs are key players …

Extracellular vesicles-encapsulated microRNA-10a-5p shed from cancer-associated fibroblast facilitates cervical squamous cell carcinoma cell angiogenesis and …

X Zhang, Y Wang, X Wang, B Zou, J Mei, X Peng… - Cancer gene …, 2021 - nature.com
Cancer-associated fibroblast (CAF) secretes extracellular vesicle (EV)-encapsulated
microRNAs (miRNAs) which have been underlined great promise for therapeutic target for …

Epigenetics of inflammatory arthritis

D Hammaker, GS Firestein - Current opinion in rheumatology, 2018 - journals.lww.com
Epigenetics of inflammatory arthritis : Current Opinion in Rheumatology Epigenetics of
inflammatory arthritis : Current Opinion in Rheumatology Log in or Register Subscribe to …

CircINHA resists granulosa cell apoptosis by upregulating CTGF as a ceRNA of miR-10a-5p in pig ovarian follicles

T Guo, J Zhang, W Yao, X Du, QQ Li, L Huang… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Mammalian ovarian follicular atresia is a complex and fine-regulated biological process with
active involvement of connective tissue growth factor (CTGF). The emergence of studies of …

Epigenetic regulation of inflammation: The metabolomics connection

S Rath, YM Hawsawi, F Alzahrani, MI Khan - Seminars in Cell & …, 2022 - Elsevier
Epigenetic factors are considered the regulator of complex machinery behind inflammatory
disorders and significantly contributed to the expression of inflammation-associated genes …

Downregulation of LncRNA OIP5-AS1 induced by IL-1β aggravates osteoarthritis via regulating miR-29b-3p/PGRN

L Zhi, J Zhao, H Zhao, Z Qing, H Liu, J Ma - Cartilage, 2021 - journals.sagepub.com
Background Long noncoding RNA (lncRNA) OIP5 antisense RNA 1 (OIP5-AS1) is an
oncogenic lncRNA; however, its role in osteoarthritis (OA) pathology still remains unknown …