Cardiovascular reactivity in cardiovascular disease:“Once more unto the breach”

SB Manuck - International Journal of Behavioral Medicine, 1994 - Springer
Discussed here are conceptual and methodologic issues that bear on the role of
bebaviorally evoked cardiovascular reactivity in cardiovascular disease. It is argued that …

Morphologic features of unstable atherothrombotic plaques underlying acute coronary syndromes

E Falk - The American journal of cardiology, 1989 - Elsevier
Unstable angina appears to be a good clinical marker for rapidly progressing coronary
artery disease. Pathologically, an unstable atherothrombotic coronary lesion, represented by …

Low-dose metoprolol CR/XL and fluvastatin slow progression of carotid intima-media thickness: main results from the β-Blocker Cholesterol-Lowering Asymptomatic …

B Hedblad, J Wikstrand, L Janzon, H Wedel… - Circulation, 2001 - Am Heart Assoc
Background—Statins reduce cardiovascular events and progression of carotid intima-media
thickness (IMT). β-Blockers are also known to reduce cardiovascular events, but less is …

Effects of metoprolol vs verapamil in patients with stable angina pectoris: The Angina Prognosis Study in Stockholm (APSIS)

N Rehnqvist, P Hjemdahl, E Billing… - European heart …, 1996 - academic.oup.com
Objective To study long-term treatment effects of metoprolol or verapamil on combined
cardiovascular end points and psychological variables in patients with stable angina …

Role of catecholamines in platelet function: pathophysiological and clinical significance

G Anfossi, M Trovati - European journal of clinical investigation, 1996 - Wiley Online Library
Platelets are involved in the pathogenesis of vascular damage in both atherosclerosis and
arterial hypertension. Their reactivity in vivo is influenced by different factors, including …

Metoprolol versus thiazide diuretics in hypertension. Morbidity results from the MAPHY Study.

J Wikstrand, I Warnold, J Tuomilehto, G Olsson… - …, 1991 - Am Heart Assoc
The present study in hypertensive men (40-64 years old) with untreated diastolic blood
pressure above 100 mm Hg was aimed at investigating whether metoprolol (n= 1,609) given …

Role of sympathoadrenal medullary activation in the initiation and progression of atherosclerosis.

JR Kaplan, K Pettersson, SB Manuck, G Olsson - Circulation, 1991 - europepmc.org
Clinical and epidemiological investigations provide evidence that psychosocial factors
influence the development of coronary heart disease and underlying atherosclerosis, an …

Are we misunderstanding beta-blockers

JM Cruickshank - International journal of cardiology, 2007 - Elsevier
In myocardial ischaemia and heart failure, beta-blockers with intrinsic sympathomimetic
activity (ISA) eg pindolol, xamoterol, bucindolol, nebivolol, have performed poorly in …

The pathogenicity of behavior and its neuroendocrine mediation: An example from coronary artery disease

SB Manuck, AL Marsland, JR Kaplan… - Psychosomatic …, 1995 - journals.lww.com
Although it is frequently hypothesized that pertubations of the body's principal axes of
neuroendocrine response, especially the sympathetic-adrenomedullary and pituitary …

Dehydroepiandrosterone feeding prevents aortic fatty streak formation and cholesterol accumulation in cholesterol-fed rabbit.

Y Arad, JJ Badimon, L Badimon… - … : An Official Journal of …, 1989 - Am Heart Assoc
The concentration of dehydroepiandrosterone sulfate (DHEA-S) in human plasma is higher
than any other steroid. Recent evidence has suggested an inverse relationship between …