Cardiac Reverse Remodeling in Ischemic Heart Disease with Novel Therapies for Heart Failure with Reduced Ejection Fraction

SA Leancă, I Afrăsânie, D Crișu, IT Matei, ȘT Duca… - Life, 2023 - mdpi.com
Despite the improvements in the treatment of coronary artery disease (CAD) and acute
myocardial infarction (MI) over the past 20 years, ischemic heart disease (IHD) continues to …

[HTML][HTML] The emerging role of sacubitril/valsartan in pulmonary hypertension with heart failure

Y Xu, B Yang, J Hui, C Zhang, X Bian, M Tao… - Frontiers in …, 2023 - frontiersin.org
Pulmonary hypertension due to left heart disease (PH-LHD) represents approximately 65-
80% of all patients with PH. The progression, prognosis, and mortality of individuals with left …

Real-world comparative effectiveness of ARNI versus ACEi/ARB in HF with reduced or mildly reduced ejection fraction

M Fu, A Pivodic, O Käck, M Costa-Scharplatz… - Clinical Research in …, 2023 - Springer
Aims Sacubitril/valsartan is a first-in-class angiotensin receptor–neprilysin inhibitor (ARNI)
with a class-1 guideline recommendation. We assessed the real-world effectiveness of ARNI …

The efficacy and safety of sacubitril/valsartan compared with ACEI/ARB in the treatment of heart failure following acute myocardial infarction: a systematic review and …

J Gao, X Zhang, M Xu, S Deng, X Chen - Frontiers in Pharmacology, 2023 - frontiersin.org
Purpose: To systematically assess the efficacy and safety of sacubitril/valsartan (SV) by
comparison with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor …

[HTML][HTML] Doxorubicin-induced cardiotoxicity and risk factors

C Belger, C Abrahams, A Imamdin, S Lecour - IJC Heart & Vasculature, 2024 - Elsevier
Doxorubicin (DOX) is an anthracycline antibiotic widely used as a chemotherapeutic agent
to treat solid tumours and hematologic malignancies. Although useful in the treatment of …

Sacubitril/Valsartan Alleviates Cardiac Remodeling and Dysfunction in L-NAME-Induced Hypertension and Hypertensive Heart Disease

P Stanko, K Repova, T Baka, K Krajcirovicova… - Biomedicines, 2024 - mdpi.com
There is ample evidence on the benefit of angiotensin receptor-neprilysin inhibitors (ARNIs)
in heart failure, yet data regarding the potential protective action of ARNIs in hypertensive …

Dapagliflozin versus sacubitril–valsartan for heart failure with mildly reduced or preserved ejection fraction

R Arbel, AN Azab, M Oberoi, E Aboalhasan… - Frontiers in …, 2024 - frontiersin.org
Background and aim: Heart failure with preserved ejection fraction (HFpEF) is associated
with an increased risk of heart failure (HF) hospitalizations and cardiovascular death (CVD) …

Relevant adverse events and drug discontinuation of Sacubitril/valsartan in a real-world Japanese cohort: REVIEW-HF registry

S Matsumoto, JJV McMurray, T Nasu, S Ishii… - Journal of …, 2023 - Elsevier
Background The characteristics, tolerability, and outcomes in patients with heart failure (HF)
who are treated with sacubitril/valsartan remain unclear in Japan. Methods We conducted a …

[HTML][HTML] Effect of sacubitril-valsartan on left ventricular remodeling and NT-proBNP in patients with heart failure complicated with hypertension and reduced ejection …

B Xie, Q Gao, Y Wang, J Du, Y He - American Journal of …, 2024 - ncbi.nlm.nih.gov
Objective: To analyze the effect of sacubitril-valsartan on left ventricular remodeling and NT-
proBNP in heart failure patients with hypertension and reduced ejection fraction. Method: A …

Kardiovaskuläre Pharmakotherapie im Alter

M Schulz, D Trenk, U Laufs - Herz, 2023 - Springer
Kardiovaskuläre Erkrankungen stellen die häufigste Ursache für Behinderung und Tod dar.
Evidenzbasierte Pharmakotherapie ist die Basis zur erfolgreichen Therapie der …