The well-developed synthetic chemistry of ruthenium, particularly with ammine, amine and
imine ligands, provides for many approaches to innovative new metallopharmaceuticals …

adrenergic transmitter (norepinephrine), serotonin; cholinergic transmitter (acetylcholine);
inhibitory (γ-aminobutyric acid) and excitatory (glutamate) amino acids; opioid and …

Specialized receptors belonging to the transient receptor potential (TRP) family of ligand-
gated ion channels constitute the critical detectors and transducers of pain-causing stimuli …

Hot peppers, also called chilli, chilli pepper, or paprika of the plant genus Capsicum (family
Solanaceae), are one of the most used vegetables and spices worldwide. Capsaicin (8 …

The present invention provides a method for the use of at least one serotype or a
combination of serotypes of Botulinum neurotoxin either alone or in combination with other …

The intradermal (id) injection of NK1 receptor antagonists GR 82334 and FK 888 (1–50
pmol/paw), in association with formalin, produced graded inhibition of the early but not the …

Capsaicin, the active ingredient in hot chilli peppers, has selective actions on unmyelinated
C-fibres and thinly myelinated A primary sensory neurones [37, 100](Table 1). Most …

Complex regional pain syndromes (CRPS) and neuropathic pain are often poorly controlled
by conventional pharmacologic interventions. We administered 8-methyl-N-vanillyl-6 …

Introduction Diabetes is an increasingly prevalent disorder affecting nearly 1-in-5 adults, of
which half will experience diabetic peripheral neuropathy (DPN) and a quarter will suffer …

Zusammenfassung Einleitung: Nozizeptoren sind Sinnesrezeptoren für noxische (den
Organismus schädigende oder bedrohende) Stimuli. Sie gehören zu den langsam leitenden …