Muntingia calabura L.(family Elaeocarpaceae) has been traditionally used to relieve various
pain‐related ailments. The present study aimed to determine the antinociceptive activity of …

TRPV1 is a channel expressed highly in small sensory neurons. TRPV1 is a ligand-gated,
cation channel that is activated by heat, acid and capsaicin, a principal ingredient in hot …

Background: Topical capsaicin is known to be a safe and effective pain management
adjunct for rheumatoid arthritis, osteoarthritis, neuralgias, and diabetic neuropathy …

Selective blockade of nociceptive pathways represents a mechanism-based approach that
has attracted a large variety of pharmacological and molecular investigations. A potential …

Resistant starch (RS) is fermentable dietary fiber. Inclusion of RS in the diet causes
decreased body fat accumulation and altered gut hormone profile. This study investigates …

Capsaicin, the active substance in chilli peppers, activates the vanilloid type 1 receptor
(VR1) rather than the vanilloid‐like receptor (VRL1) in the trigeminal ganglion and nucleus …

The exercise pressor reflex (EPR) is comprised of group III and IV skeletal muscle afferents
and is one of the principal mediators of the cardiovascular response to exercise. In animals …

The use of chemical insecticides in crop production has resulted in increased food
production in Africa, but their use has resulted in the destruction of beneficial organisms and …

Arvanil, a structural “hybrid” between the endogenous cannabinoid CB1 receptor ligand
anandamide and capsaicin, is a potent agonist for the capsaicin receptor VR1 (vanilloid …

Agastache mexicana is a plant that has long been used in large demands in Mexican folk
medicine to treat anxiety, insomnia and pain, among others affections. Chromatographic …