Resiniferatoxin (RTX) is an ultrapotent capsaicin analog that binds to the transient receptor
potential channel, vanilloid subfamily member 1 (TRPV1). There is a large body of evidence …

The deregulation of dietary supplements and natural products marketing by the FDA has
widened the natural products market in Europe and worldwide. While the discussion about …

Pain is a common reason for physician appointments for all age groups. 13 Although it is
described as an unpleasant sensory and emotional experience, pain is a complex …

The possible modulatory role of nitric oxide (NO) in neurogenic edema formation in rat paw
skin, induced by electrical stimulation of the saphenous nerve, was investigated by using …

F or Bentham, the study of pleasures and pains was the study of hedonic feelings. All good
feelings were pleasures, and “pain” could describe all that humankind sought to avoid …

The discharge of single afferent units recorded from filaments of the mixed ciliary nerve of
anaesthetised cats was used to study the effects of CO 2, capsaicin and the capsaicin …

The effect of a single subcutaneous (sc) injection of the ultrapotent capsaicin analogue
resiniferatoxin (RTX) on responses of adult rats to noxious thermal and mechanical …

Nitro-oleic acid (OA-NO2), an electrophilic fatty acid by-product of nitric oxide and nitrite
reactions, is present in normal and inflamed mammalian tissues at up to micromolar …

Transdermal route is the most convenient route for the delivery of drug having short
biological half life and poorly soluble drugs. This route provides many advantages over …

Pharmacotherapy of Osteoarthritis : American Journal of Physical Medicine & Rehabilitation
Pharmacotherapy of Osteoarthritis : American Journal of Physical Medicine & Rehabilitation …