[HTML][HTML] Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

[HTML][HTML] Advances in human oxytocin measurement: challenges and proposed solutions

BA Tabak, G Leng, A Szeto, KJ Parker… - Molecular …, 2023 - nature.com
Oxytocin, a neuropeptide known for its role in reproduction and socioemotional processes,
may hold promise as a therapeutic agent in treating social impairments in patient …

[HTML][HTML] RAGE regulates oxytocin transport into the brain

Y Yamamoto, H Higashida - Communications biology, 2020 - nature.com
Oxytocin, a nonapeptide hormone, has a key role in female reproductive functions as well as
in social memory in the brain. In our recent Communications Biology article, we reported that …

[HTML][HTML] Imaging of intranasal drug delivery to the brain

MC Veronesi, M Alhamami, SB Miedema… - American journal of …, 2020 - ncbi.nlm.nih.gov
Intranasal (IN) delivery is a rapidly developing area for therapies with great potential for the
treatment of central nervous system (CNS) diseases. Moreover, in vivo imaging is becoming …

[HTML][HTML] Prolactin and oxytocin: potential targets for migraine treatment

AK Szewczyk, S Ulutas, T Aktürk, L Al-Hassany… - The Journal of …, 2023 - Springer
Migraine is a severe neurovascular disorder of which the pathophysiology is not yet fully
understood. Besides the role of inflammatory mediators that interact with the …

[HTML][HTML] The effects of oxytocin on appetite regulation, food intake and metabolism in humans

L Kerem, EA Lawson - International Journal of Molecular Sciences, 2021 - mdpi.com
The hypothalamic peptide oxytocin and its receptor are involved in a range of physiological
processes, including parturition, lactation, cell growth, wound healing, and social behavior …

[HTML][HTML] Crosstalk between schizophrenia and metabolic syndrome: The role of oxytocinergic dysfunction

KK Goh, CYA Chen, TH Wu, CH Chen… - International journal of …, 2022 - mdpi.com
The high prevalence of metabolic syndrome in persons with schizophrenia has spurred
investigational efforts to study the mechanism beneath its pathophysiology. Early psychosis …

Heterogeneity in response to repeated intranasal oxytocin in schizophrenia and autism spectrum disorders: A meta‐analysis of variance

D Martins, M Paduraru… - British Journal of …, 2022 - Wiley Online Library
Intranasal oxytocin (OT) has been suggested as a putative adjunctive treatment for patients
with schizophrenia and autism spectrum disorders (ASD). Here, we examine available …

[HTML][HTML] Chronic oxytocin administration stimulates the oxytocinergic system in children with autism

M Moerkerke, N Daniels, L Tibermont, T Tang… - Nature …, 2024 - nature.com
Clinical efficacy of intranasal administration of oxytocin is increasingly explored in autism
spectrum disorder, but to date, the biological effects of chronic administration regimes on …

Anxiolytic effects of chronic intranasal oxytocin on neural responses to threat are dose-frequency dependent

J Kou, Y Zhang, F Zhou, Z Gao, S Yao… - Psychotherapy and …, 2022 - karger.com
Introduction: Anxiety disorders are prevalent mental conditions characterized by
exaggerated anxious arousal and threat reactivity. Animal and human studies suggest an …