Effects of intranasal oxytocin on pain perception among human subjects: A systematic literature review and meta-analysis

S Lopes, F de Lima Osório - Hormones and Behavior, 2023 - Elsevier
Introduction Oxytocin (OXT) is a peptide hormone produced in the hypothalamus that plays a
neuromodulatory role in emotion, stress, and anxiety. Due to its multidimensional role, OXT …

The effect of Oxytocin administration on patient-therapist alliance congruence: Results from a randomized controlled trial

A Grossman-Giron, H Fisher, D Atzil-Slonim… - Psychotherapy …, 2023 - Taylor & Francis
Objectives The effects of oxytocin (OT) administration on psychotherapeutic processes have
thus far been elusive. This study explored the effect of OT administration on patient-therapist …

Chronic oxytocin improves neural decoupling at rest in children with autism: an exploratory RCT

K Alaerts, M Moerkerke, N Daniels… - Journal of Child …, 2024 - Wiley Online Library
Background Shifts in peak frequencies of oscillatory neural rhythms are put forward as a
principal mechanism by which cross‐frequency coupling/decoupling is implemented in the …

Age and intranasal oxytocin effects on trust-related decisions after breach of trust: Behavioral and brain evidence.

I Frazier, T Lin, P Liu, S Skarsten, D Feifel… - Psychology and …, 2021 - psycnet.apa.org
Age-related differences in cognition and socioemotional functions, and in associated brain
regions, may reduce sensitivity to cues of untrustworthiness, with effects on trust-related …

[HTML][HTML] Safety and tolerability of chronic intranasal oxytocin in older men: results from a randomized controlled trial

JM Rung, M Horta, EM Tammi, E Perez, MC Ojeda… - …, 2021 - Springer
Rationale Most studies evaluating the safety and tolerability of intranasal oxytocin (OT) have
not reported consistent adverse events (AEs), but they have largely focused on young men …

[HTML][HTML] Oxytocin: A multi-functional biomolecule with potential actions in dysfunctional conditions; from animal studies and beyond

AS Tsingotjidou - Biomolecules, 2022 - mdpi.com
Oxytocin is a hormone secreted from definite neuroendocrine neurons located in specific
nuclei in the hypothalamus (mainly from paraventricular and supraoptic nuclei), and its main …

Innovations in Geroscience to enhance mobility in older adults

SD Anton, Y Cruz-Almeida, A Singh, J Alpert… - Experimental …, 2020 - Elsevier
Aging is the primary risk factor for functional decline; thus, understanding and preventing
disability among older adults has emerged as an important public health challenge of the …

[HTML][HTML] Effects of single-and multiple-dose oxytocin treatment on amygdala low-frequency BOLD fluctuations and BOLD spectral dynamics in autism

K Alaerts, S Bernaerts, N Wenderoth - Translational Psychiatry, 2022 - nature.com
Prior neuroimaging clinical trials investigating the neural effects of intranasal administration
of the neuropeptide oxytocin demonstrated a key role of the amygdala in oxytocin's …

[HTML][HTML] Age-dependent effects of oxytocin in brain regions enriched with oxytocin receptors

S Xiao, NC Ebner, A Manzouri, TQ Li, DS Cortes… - …, 2024 - Elsevier
Although intranasal oxytocin administration to tap into central functions is the most
commonly used non-invasive means for exploring oxytocin's role in human cognition and …

Effects of chronic intranasal oxytocin on visual attention to faces vs. natural scenes in older adults

A Shoenfelt, D Pehlivanoglu, T Lin, M Ziaei… - …, 2024 - Elsevier
Aging is associated with changes in face processing, including desensitization to face cues
like gaze direction and an attentional preference to faces with positive over negative …