Prenatal exposure to valproic acid and treatment with intranasal oxytocin have sex-specific effects on behavior in Long Evans rats

SM Harding, EC Masters, CM D'Agata… - Behavioural …, 2021 - journals.lww.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits
in social behaviors and communication. In rodents and humans, prenatal exposure to …

Aging online:: Rethinking the aging decision-maker in a digital era

NC Ebner, D Pehlivanoglu, R Polk, GR Turner… - A fresh look at …, 2022 - taylorfrancis.com
The rapid shift toward a digitalized, globally connected world confronts the aging individual
with drastically new contexts and decisions. This chapter sheds light on the aging decision …

Emerging therapeutic landscape on delivery of oxytocin to brain for treating neurological disorders

S Kumar, NK Garg, A Jain, P Pandey… - Journal of Drug Delivery …, 2024 - Elsevier
Neurological ailments constitute a substantial cause of disability and death. There are
several treatments to manage neurological disorders, employing both synthesized …

Intranasal oxytocin as an adjunct treatment among patients with severe major depression with and without comorbid borderline personality disorder

H Maoz, A Grossman-Giron, O Sedoff, U Nitzan… - Journal of Affective …, 2024 - Elsevier
Introduction Results of studies concerning a possible beneficial effect of Intranasal-Oxytocin
(IN-OT) as an add-on treatment for patients with major depression (MDD) have been …

[HTML][HTML] Transcriptome analysis identifies an ASD-Like phenotype in oligodendrocytes and microglia from C58/J amygdala that is dependent on sex and sociability

GD Dalton, SK Siecinski, VD Nikolova, GP Cofer… - Behavioral and Brain …, 2024 - Springer
Abstract Background Autism Spectrum Disorder (ASD) is a group of neurodevelopmental
disorders with higher incidence in males and is characterized by atypical verbal/nonverbal …

Social functioning predicts individual changes in EEG microstates following intranasal oxytocin administration: A double‐blind, cross‐over randomized clinical trial

MI Tomescu, S Van der Donck, EM Perisanu… - …, 2024 - Wiley Online Library
Oxytocin (OXT) modulates social behaviors. However, the administration of exogenous OXT
in humans produces inconsistent behavioral changes, affecting future consideration of OXT …

[HTML][HTML] Chronic intranasal oxytocin increases acoustic eavesdropping and adult neurogenesis

PK Monari, ZJ Herro, J Bymers, CA Marler - Hormones and Behavior, 2023 - Elsevier
Social information gathering is a complex process influenced by neuroendocrine-modulated
neural plasticity. Oxytocin (OXT) is a key regulator of social decision-making processes such …

Four-week intranasal oxytocin administration reduces attachment avoidance in older women

KA Wright, R Polk, T Lin, D Feifel, NC Ebner - Hormones and behavior, 2023 - Elsevier
The neuropeptide oxytocin (OT) serves as a critical modulator of social cognition and social
behavior. Adult attachment is an affiliative process crucial for social interaction across …

[HTML][HTML] Changes in depressive-like behaviors induced by spinal cord injury based on the hypothalamic-pituitary-adrenal axis and hippocampal neurogenesis

CH Liu, BL Zhao, WT Li, XH Zhou, Z Jin… - Journal of Integrative …, 2021 - imrpress.com
A reduction in sucrose preference is a key characteristic of depressive-like behaviors after
spinal cord injury as judged by the sucrose preference test, the hypothalamic-pituitary …

Effects of chronically exogenous oxytocin on ovary and uterus: A comparison of intraperitoneal and intranasal administration

GE Senturk, Z Sezer, H Sahin, B Isildar, A Abdulova - Peptides, 2023 - Elsevier
Oxytocin (OT) has been studied as a therapeutic neuropeptide in various diseases, but its
effect on the ovary and uterus is not fully known. This study investigates the effects of …