Managing nonalcoholic fatty liver disease in patients living with HIV

ZH Tafesh, EC Verna - Current opinion in infectious diseases, 2017 - journals.lww.com
Managing nonalcoholic fatty liver disease in patients living... : Current Opinion in Infectious
Diseases Managing nonalcoholic fatty liver disease in patients living with HIV : Current …

Activity profiles of deoxynucleoside kinases and 5′-nucleotidases in cultured adipocytes and myoblastic cells: insights into mitochondrial toxicity of nucleoside …

SN Rylova, F Albertioni, G Flygh, S Eriksson - Biochemical pharmacology, 2005 - Elsevier
Nucleoside reverse transcriptase inhibitor (NRTI) treatment of HIV is associated with
complications, including lipodystrophy (LD) and myopathy. Inhibition of mitochondrial DNA …

Uracyl spirooxetane nucleosides

IN Houpis, THM Jonckers, PJMB Raboisson… - US Patent …, 2016 - Google Patents
The present invention relates to compounds of the formula I: including any possible
stereoisomers thereof, wherein Rhas the meaning as defined herein, or a pharmaceutically …

Mitochondrial DNA levels in fat and blood cells from patients with lipodystrophy or peripheral neuropathy and the effect of 90 days of high-dose coenzyme Q treatment …

ER Christensen, M Stegger… - Clinical Infectious …, 2004 - academic.oup.com
Background. Mitochondrial toxicity can be induced by reverse-transcriptase inhibitors, and
an association between levels of mitochondrial DNA (mtDNA) per cell and lipodystrophy …

Rapid analysis of mitochondrial DNA depletion by fluorescence in situ hybridization and immunocytochemistry: potential strategies for HIV therapeutic monitoring

MS Janes, BJ Hanson, DM Hill… - … of Histochemistry & …, 2004 - journals.sagepub.com
Nucleoside reverse transcriptase inhibitors (NRTIs) have been a mainstay in the treatment of
human immunodeficiency virus since the introduction of azidothymidine (AZT) in 1987 …

Peripheral neuropathies in human immunodeficiency virus infection

A Höke, DR Cornblath - Supplements to Clinical neurophysiology, 2004 - Elsevier
Publisher Summary This chapter discusses the various peripheral neuropathies in human
immunodeficiency virus (HIV) infection, including HIV-associated sensory neuropathies (HIV …

Acetyl‐l‐carnitine and nucleoside reverse transcriptase inhibitor‐associated neuropathy in HIV infection

V Valcour, TM Yeh, R Bartt, D Clifford… - HIV …, 2009 - Wiley Online Library
Objectives Antiretroviral toxic neuropathy (ATN) is associated with dideoxynucleoside
reverse transcriptase inhibitor use in patients infected with HIV, possibly as a result of …

Inhibition of highly productive HIV-1 infection in T cells, primary human macrophages, microglia, and astrocytes by Sargassum fusiforme

EE Paskaleva, X Lin, W Li, R Cotter, MT Klein… - AIDS Research and …, 2006 - Springer
Background The high rate of HIV-1 mutation and increasing resistance to currently available
antiretroviral (ART) therapies highlight the need for new antiviral agents. Products derived …

Substituted nucleosides, nucleotides and analogs thereof

L Beigelman, G Wang, DB Smith - US Patent 10,112,966, 2018 - Google Patents
US10112966B2 - Substituted nucleosides, nucleotides and analogs thereof - Google
Patents US10112966B2 - Substituted nucleosides, nucleotides and analogs thereof …

[HTML][HTML] Optimizing Cardiometabolic Risk in People Living with Human Immunodeficiency Virus: A Deep Dive into an Important Risk Enhancer

EA Kobe, A Thakkar, S Matai, E Akkaya… - American Journal of …, 2024 - Elsevier
Effective antiretroviral therapy (ART) is now nearly ubiquitous. However, the survival benefits
conferred with ART contribute to an aging human immunodeficiency virus (HIV) population …