Since the ancient times, bee products (ie, honey, propolis, pollen, bee venom, bee bread,
and royal jelly) have been considered as natural remedies with therapeutic effects against a …

Diabetic nephropathy (DN) is a renal complication of diabetic hyperglycemia. The Signal
transducer and activator of transcription 3 (Stat3) is a center molecule of the chronic …

The pathogenesis of diabetic nephropathy (DN) involves cellular activation of oxidative
stress and inflammation. Eriodictyol is a citrus-derived flavonoid with multiple …

LCZ696 (valsartan/sacubitril) has the potential to slow the progression of diabetic kidney
disease (DKD) according to previous reports. However, the renoprotective mechanism …

The use of cisplatin, a chemotherapy drug, is often limited due to its renal side effects such
as acute kidney injury (AKI). However, there are no validated medications to prevent or treat …

Chronic kidney disease (CKD) is a chronic and progressive systemic condition that
characterizes irreversible alterations in the kidneys' function and structure over an extended …

Background Artemisinin (ART) is a safe and effective antimalarial drug. In recent years,
antimalarial drugs have demonstrated a good therapeutic efficacy in IgA nephropathy …

Objective: This research investigated secoisolariciresinol diglucoside (SDG) flax extract
effects on apoptosis, hedgehog (Hh), autophagy, and the anti-oxidation process in …

The aim of the current work was to examine for the first time the nephropreventive capacity of
Ephedra alata seed extract (E) against maternal exposure to acephate in rat offspring. The in …

Renal fibrosis is a chronic pathological process that seriously endangers human health.
However, the current therapeutic options for this disease are extremely limited. Previous …