Sleep, sleep deprivation, autonomic nervous system and cardiovascular diseases

E Tobaldini, G Costantino, M Solbiati, C Cogliati… - Neuroscience & …, 2017 - Elsevier
Sleep deprivation (SD) has become a relevant health problem in modern societies. We can
be sleep deprived due to lifestyle habits or due to sleep disorders, such as insomnia …

Obstructive sleep apnea: personal, societal, public health, and legal implications

NE Morsy, NS Farrag, NFW Zaki… - Reviews on …, 2019 - degruyter.com
Introduction Obstructive sleep apnea (OSA) is a widely prevalent sleep-related breathing
disorder, which leads to several life-threatening diseases. OSA has systemic effects on …

Heart failure and sleep disorders

G Parati, C Lombardi, F Castagna… - Nature Reviews …, 2016 - nature.com
Awareness of the importance of sleep-related disorders in patients with cardiovascular
diseases is growing. In particular, sleep-disordered breathing, short sleep time, and low …

Nonclinical cardiovascular assessment of the soluble guanylate cyclase stimulator vericiguat

H Himmel, A Lagrutta, M Vömel, RP Amin… - … of Pharmacology and …, 2023 - ASPET
Vericiguat and its metabolite M-1 were assessed for proarrhythmic risk in nonclinical in vitro
and in vivo studies. In vitro manual voltage-clamp recordings at room temperature …

Obstructive sleep apnea and cardiac arrhythmias: a contemporary review

B Laczay, MD Faulx - Journal of Clinical Medicine, 2021 - mdpi.com
Obstructive sleep apnea (OSA) is a highly prevalent disorder with a growing incidence
worldwide that closely mirrors the global obesity epidemic. OSA is associated with …

[HTML][HTML] Central and obstructive apneas in heart failure with reduced, mid-range and preserved ejection fraction

C Borrelli, F Gentile, P Sciarrone, G Mirizzi… - Frontiers in …, 2019 - frontiersin.org
Background: Although central apneas (CA) and obstructive apneas (OA) are highly
prevalent in heart failure (HF), a comparison of apnea prevalence, predictors and clinical …

Cardiac arrhythmias and sleep-disordered breathing in patients with heart failure

W Grimm, U Koehler - International journal of molecular sciences, 2014 - mdpi.com
The relationship between heart failure (HF), sleep-disordered breathing and cardiac
arrhythmias is complex and poorly understood. Whereas the frequency of predominantly …

An update on cardiovascular effects of obstructive sleep apnoea syndrome

M Uyar, V Davutoglu - Postgraduate medical journal, 2016 - academic.oup.com
Obstructive sleep apnoea syndrome is an important health problem which may cause or
worsen systemic diseases. Chronic intermittent hypoxia during repetitive airflow cessations …

Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy

T Sofer, R Li, R Joehanes, H Lin, AC Gower, H Wang… - …, 2020 - thelancet.com
Abstract Background Sleep Disordered Breathing (SDB) is associated with a wide range of
pathophysiological changes due, in part, to hypoxemia during sleep. We sought to identify …

The effects of sleep deprivation on microRNA expression in rats submitted to pilocarpine-induced status epilepticus

G Matos, FA Scorza, DR Mazzotti, C Guindalini… - Progress in Neuro …, 2014 - Elsevier
Epilepsy is a neurological disorder with significant prevalence and the individuals affected
by this disease have a great probability of occurrence of a lethal phenomenon known as …