Microvascular endothelial cells in the kidney have been a neglected cell type in sepsis-
induced acute kidney injury (sepsis-AKI) research; yet, they offer tremendous potential as …

Summary 2018 was the year of the first marketing authorization of an allogeneic stem cell
therapy by the European Medicines Agency. The authorization concerns the use of …

Abstract The coronavirus disease 2019 (COVID-19) pandemic has grown to be a global
public health crisis with no safe and effective treatments available yet. Recent findings …

Mesenchymal stromal (stem) cells (MSCs) have multipotent differentiation capacity and exist
in nearly all forms of post-natal organs and tissues. The immunosuppressive and anti …

Human umbilical cord mesenchymal stem cell-derived exosomes (HucMSC-Ex) are a
promising tool for the repair of acute kidney injury (AKI) caused by cisplatin and …

Background Sepsis is a debilitating systemic inflammation that resulted from infection or
injury. Despite many advances in treatment, the resulting mortality rate has remained high …

Acute kidney injury (AKI), characterized by a sharp drop in glomerular filtration, continues to
be a significant health burden because it is associated with high initial mortality, morbidity …

Introduction: Mesenchymal stromal (stem) cell (MSC) therapies are emerging as a promising
therapeutic intervention in patients with Acute Respiratory Distress Syndrome (ARDS) and …

Umbilical cord Wharton's jelly‐derived mesenchymal stem cells (WJ‐MSCs) have recently
gained considerable attention in the field of regenerative medicine. Their high proliferation …

Sepsis is a heterogenous and highly complex clinical syndrome, which is caused by
infectious or noninfectious factors. Acute kidney injury (AKI) is one of the most common and …