[HTML][HTML] Increased prevalence of hybrid epithelial/mesenchymal state and enhanced phenotypic heterogeneity in basal breast cancer

S Sahoo, S Ramu, MG Nair, M Pillai, BP San Juan… - Iscience, 2024 - cell.com
Intra-tumoral phenotypic heterogeneity promotes tumor relapse and therapeutic resistance
and remains an unsolved clinical challenge. Decoding the interconnections among different …

A synthetic lethal screen for Snail-induced enzalutamide resistance identifies JAK/STAT signaling as a therapeutic vulnerability in prostate cancer

KE Ware, BC Thomas, PD Olawuni… - Frontiers in Molecular …, 2023 - frontiersin.org
Despite substantial improvements in the treatment landscape of prostate cancer, the
evolution of hormone therapy-resistant and metastatic prostate cancer remains a major …

[HTML][HTML] Multi-modal transcriptomic analysis unravels enrichment of hybrid epithelial/mesenchymal state and enhanced phenotypic heterogeneity in basal breast …

S Sahoo, S Ramu, MG Nair, M Pillai, BP San Juan… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Intra-tumoral phenotypic heterogeneity promotes tumor relapse and therapeutic resistance
and remains an unsolved clinical challenge. It manifests along multiple phenotypic axes and …

Establishment and characterization of the gemcitabine-resistant human gallbladder cancer cell line NOZ GemR

M Xu, S Xu, B Jiang, Z Man - Annals of Medicine and Surgery, 2024 - journals.lww.com
Background: Patients with gallbladder cancer (GBC) generally receive gemcitabine as the
standard treatment; however, its efficacy is often limited owing to the development of …