Abstract Background Mesenchymal stem cells (MSCs) have been shown to alleviate acute
lung injury (ALI) via paracrine hepatocyte growth factor (HGF) and to induce the …

Objectives Acute lung injury (ALI) remains a common cause of morbidity and mortality
worldwide, and to date, there is no effective treatment for ALI. Previous studies have …

Background The authors hypothesized that low tidal volume (VT) would minimize ventilator-
induced lung injury regardless of the degree of mechanical power. The authors investigated …

Tidal volume (VT) has been considered the main determinant of ventilator-induced lung
injury (VILI). Recently, experimental studies have suggested that mechanical power …

Background Gradually changing respiratory rate (RR) during time to reduce ventilation-
induced lung injury has not been investigated. The authors hypothesized that gradual …

Purpose Dexmedetomidine (DEX) has been associated with inflammation, oxidative stress,
and apoptosis, but its effects on lipopolysaccharide (LPS)-induced lung injury remain …

BACKGROUND: Intraoperative mechanical ventilation may yield lung injury. To date, there
is no consensus regarding the best ventilator strategy for abdominal surgery. We aimed to …

Obese patients are at higher risk of developing acute respiratory distress syndrome (ARDS);
however, their survival rates are also higher compared to those of similarly ill non-obese …

Objectives: To compare a time-controlled adaptive ventilation strategy, set in airway
pressure release ventilation mode, versus a protective mechanical ventilation strategy in …

BACKGROUND Harmful effects of spontaneous breathing have been shown in experimental
severe acute respiratory distress syndrome (ARDS). However, in the clinical setting …