Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD
DA Ferenbach, JV Bonventre - Nature Reviews Nephrology, 2015 - nature.com
Acute kidney injury is an increasingly common complication of hospital admission and is
associated with high levels of morbidity and mortality. A hypotensive, septic, or toxic insult …
associated with high levels of morbidity and mortality. A hypotensive, septic, or toxic insult …
Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy
Mesenchymal stem cells (MSCs) are adult multipotent cells that give rise to various cell
types of the mesodermal germ layer. MSCs are of great interest in the field of regenerative …
types of the mesodermal germ layer. MSCs are of great interest in the field of regenerative …
[HTML][HTML] Fibrous scaffolds potentiate the paracrine function of mesenchymal stem cells: A new dimension in cell-material interaction
While the studies on the material interaction with mesenchymal stem cells (MSCs) have
been mainly focused on the ability of materials to provide environment to regulate cell …
been mainly focused on the ability of materials to provide environment to regulate cell …
Mesenchymal stem cells attenuate renal fibrosis through immune modulation and remodeling properties in a rat remnant kidney model
P Semedo, M Correa-Costa, M Antonio Cenedeze… - Stem …, 2009 - academic.oup.com
Mesenchymal stem cells (MSCs) have regenerative properties in acute kidney injury, but
their role in chronic kidney diseases is still unknown. More specifically, it is not known …
their role in chronic kidney diseases is still unknown. More specifically, it is not known …
Mesenchymal stem cell-educated macrophages
E Eggenhofer, MJ Hoogduijn - Transplantation research, 2012 - Springer
Mesenchymal stem cells (MSC) mediate their immunosuppressive effects via a variety of
mechanisms. One of these mechanisms involves the induction of macrophages with …
mechanisms. One of these mechanisms involves the induction of macrophages with …
Human bone marrow–derived clonal mesenchymal stem cells inhibit inflammation and reduce acute pancreatitis in rats
KH Jung, SU Song, T Yi, MS Jeon, SW Hong… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Acute pancreatitis (AP) has a high mortality rate; repetitive AP
induces chronic AP and pancreatic adenocarcinoma. Mesenchymal stem cells (MSCs) have …
induces chronic AP and pancreatic adenocarcinoma. Mesenchymal stem cells (MSCs) have …
Cell-based therapy for acute organ injury: preclinical evidence and ongoing clinical trials using mesenchymal stem cells
Critically ill patients often suffer from multiple organ failures involving lung, kidney, liver, or
brain. Genomic, proteomic, and metabolomic approaches highlight common injury …
brain. Genomic, proteomic, and metabolomic approaches highlight common injury …
Mesenchymal stem cells-derived exosomes ameliorate ischemia/reperfusion induced acute kidney injury in a porcine model
J Huang, H Cao, B Cui, X Ma, L Gao, C Yu… - Frontiers in cell and …, 2022 - frontiersin.org
Exosomes are membrane-enclosed vesicles secreted by cells, containing a variety of
biologically active ingredients including proteins, nucleic acids and lipids. In this study, we …
biologically active ingredients including proteins, nucleic acids and lipids. In this study, we …
Early intervention with mesenchymal stem cells prevents nephropathy in diabetic rats by ameliorating the inflammatory microenvironment
Y Li, J Liu, G Liao, J Zhang… - International …, 2018 - spandidos-publications.com
Diabetic nephropathy (DN) is a major complication of diabetes and represents the leading
cause of end-stage renal disease. Mesenchymal stem cell (MSC) treatment has been …
cause of end-stage renal disease. Mesenchymal stem cell (MSC) treatment has been …
Human mesenchymal stem cells alter macrophage phenotype and promote regeneration via homing to the kidney following ischemia-reperfusion injury
AF Wise, TM Williams, MBG Kiewiet… - American Journal …, 2014 - journals.physiology.org
Mesenchymal stem cells (MSCs) ameliorate injury and accelerate repair in many organs,
including the kidney, although the reparative mechanisms and interaction with macrophages …
including the kidney, although the reparative mechanisms and interaction with macrophages …