Oxidative stress and its significant roles in neurodegenerative diseases and cancer

R Thanan, S Oikawa, Y Hiraku, S Ohnishi… - International journal of …, 2014 - mdpi.com
Reactive oxygen and nitrogen species have been implicated in diverse pathophysiological
conditions, including inflammation, neurodegenerative diseases and cancer. Accumulating …

Crosstalk between DNA damage and inflammation in the multiple steps of carcinogenesis

S Kawanishi, S Ohnishi, N Ma, Y Hiraku… - International journal of …, 2017 - mdpi.com
Inflammation can be induced by chronic infection, inflammatory diseases and
physicochemical factors. Chronic inflammation is estimated to contribute to approximately …

Nitric oxide and peroxynitrite in health and disease

P Pacher, JS Beckman, L Liaudet - Physiological reviews, 2007 - journals.physiology.org
The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer

N Khansari, Y Shakiba… - Recent patents on …, 2009 - ingentaconnect.com
Chronic inflammation is a pathological condition characterized by continued active
inflammation response and tissue destruction. Many of the immune cells including …

Chronic inflammation and oxidative stress in human carcinogenesis

A Federico, F Morgillo, C Tuccillo… - … journal of cancer, 2007 - Wiley Online Library
A wide array of chronic inflammatory conditions predispose susceptible cells to neoplastic
transformation. In general, the longer the inflammation persists, the higher the risk of cancer …

Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis

S Kawanishi, Y Hiraku, S Pinlaor, N Ma - 2006 - degruyter.com
Infection and chronic inflammation are proposed to contribute to carcinogenesis through
inflammation-related mechanisms. Infection with hepatitis C virus, Helicobacter pylori and …

HPV-DNA integration and carcinogenesis: putative roles for inflammation and oxidative stress

VM Williams, M Filippova, U Soto… - Future …, 2011 - Taylor & Francis
HPV-DNA integration into cellular chromatin is usually a necessary event in the
pathogenesis of HPV-related cancer; however, the mechanism of integration has not been …

DNA damage in inflammation‐related carcinogenesis and cancer stem cells

S Ohnishi, N Ma, R Thanan, S Pinlaor… - Oxidative medicine …, 2013 - Wiley Online Library
Infection and chronic inflammation have been recognized as important factors for
carcinogenesis. Under inflammatory conditions, reactive oxygen species (ROS) and reactive …

Role of nitrative and oxidative DNA damage in inflammation‐related carcinogenesis

M Murata, R Thanan, N Ma… - BioMed Research …, 2012 - Wiley Online Library
Chronic inflammation induced by biological, chemical, and physical factors has been found
to be associated with the increased risk of cancer in various organs. We revealed that …

Nitrative and oxidative DNA damage in infection-related carcinogenesis in relation to cancer stem cells

S Kawanishi, S Ohnishi, N Ma, Y Hiraku… - Genes and …, 2016 - Springer
Infection and chronic inflammation have been recognized as important factors for
carcinogenesis. Under inflammatory conditions, reactive oxygen species (ROS) and reactive …