Cu (I)-catalyzed click chemistry in glycoscience and their diverse applications
Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …
Bioorthogonal chemistry
SL Scinto, DA Bilodeau, R Hincapie, W Lee… - Nature Reviews …, 2021 - nature.com
Bioorthogonal chemistry represents a class of high-yielding chemical reactions that proceed
rapidly and selectively in biological environments without side reactions towards …
rapidly and selectively in biological environments without side reactions towards …
A hitchhiker's guide to click-chemistry with nucleic acids
NZ Fantoni, AH El-Sagheer, T Brown - Chemical Reviews, 2021 - ACS Publications
Click chemistry is an immensely powerful technique for the fast and efficient covalent
conjugation of molecular entities. Its broad scope has positively impacted on multiple …
conjugation of molecular entities. Its broad scope has positively impacted on multiple …
Cu-catalyzed click reaction in carbohydrate chemistry
Cu (I)-catalyzed azide–alkyne 1, 3-dipolar cycloaddition (CuAAC), popularly known as the
“click reaction”, serves as the most potent and highly dependable tool for facile construction …
“click reaction”, serves as the most potent and highly dependable tool for facile construction …
Macrocyclization strategies for cyclic peptides and peptidomimetics
C Bechtler, C Lamers - RSC Medicinal Chemistry, 2021 - pubs.rsc.org
Peptides are a growing therapeutic class due to their unique spatial characteristics that can
target traditionally “undruggable” protein–protein interactions and surfaces. Despite their …
target traditionally “undruggable” protein–protein interactions and surfaces. Despite their …
Copper-catalysed azide–alkyne cycloadditions (CuAAC): an update
E Haldón, MC Nicasio, PJ Pérez - Organic & Biomolecular Chemistry, 2015 - pubs.rsc.org
The reactions of organic azides and alkynes catalysed by copper species represent the
prototypical examples of click chemistry. The so-called CuAAC reaction (copper-catalysed …
prototypical examples of click chemistry. The so-called CuAAC reaction (copper-catalysed …
Click chemistry in complex mixtures: bioorthogonal bioconjugation
The selective chemical modification of biological molecules drives a good portion of modern
drug development and fundamental biological research. While a few early examples of …
drug development and fundamental biological research. While a few early examples of …
The CuAAC: Principles, homogeneous and heterogeneous catalysts, and novel developments and applications
S Neumann, M Biewend, S Rana… - Macromolecular Rapid …, 2020 - Wiley Online Library
The copper‐catalyzed azide/alkyne cycloaddition reaction (CuAAC) has emerged as the
most useful “click” chemistry. Polymer science has profited enormously from CuAAC by its …
most useful “click” chemistry. Polymer science has profited enormously from CuAAC by its …
Functionalizing nanoparticles with biological molecules: developing chemistries that facilitate nanotechnology
KE Sapsford, WR Algar, L Berti, KB Gemmill… - Chemical …, 2013 - ACS Publications
Bionanotechnology has now become firmly established in its own right as one of the
principle and focused subdisciplines within nanotechnology.(1-10) Bionanotechnology can …
principle and focused subdisciplines within nanotechnology.(1-10) Bionanotechnology can …