Summary Background Potentially untreatable Plasmodium falciparum malaria threatens the
Greater Mekong subregion. A previous series of pilot projects in Myanmar, Laos, Cambodia …

Understanding the importance of gametocyte density on human-to-mosquito transmission is
of immediate relevance to malaria control. Previous work (Churcher et al., 2013) indicated a …

Background Submicroscopic malaria infections contribute to transmission in exposed
populations but their extent is underestimated even by standard molecular diagnostics …

Infection with Plasmodium can elicit antibodies that inhibit parasite survival in the mosquito,
when they are ingested in an infectious blood meal. Here, we determine the transmission …

Background Effective targeting and evaluation of interventions that protect against adult
malaria vectors requires an understanding of how gaps in personal protection arise. An …

Achieving malaria elimination requires a better understanding of the transmissibility of
human infections in different transmission settings. This study aimed to characterize the …

Malaria control may be enhanced by targeting reservoirs of Plasmodium falciparum
transmission. One putative reservoir is asymptomatic malaria infections and the scale of their …

Plasmodium sexual differentiation is required for malaria transmission, yet much remains
unknown about its regulation. Here, we quantify early gametocyte-committed ring (gc-ring) …

Heterogeneity in transmission is a challenge for infectious disease dynamics and control. An
80-20 “Pareto” rule has been proposed to describe this heterogeneity whereby 80% of …

The human infectious reservoir of Plasmodium falciparum is governed by transmission
efficiency during vector-human contact and mosquito biting preferences. Understanding …