Extracellular vesicles in immunomodulation and tumor progression
Extracellular vesicles have emerged as prominent regulators of the immune response
during tumor progression. EVs contain a diverse repertoire of molecular cargo that plays a …
during tumor progression. EVs contain a diverse repertoire of molecular cargo that plays a …
Recent applications of immunomodulatory biomaterials for disease immunotherapy
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …
Targeting cancer stem cell pathways for cancer therapy
L Yang, P Shi, G Zhao, J Xu, W Peng, J Zhang… - Signal transduction and …, 2020 - nature.com
Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …
Exosomes and cancer-Diagnostic and prognostic biomarkers and therapeutic vehicle
X Wang, L Tian, J Lu, IOL Ng - Oncogenesis, 2022 - nature.com
Exosomes belong to a subpopulation of extracellular vesicles secreted by the dynamic
multistep endocytosis process and carry diverse functional molecular cargoes, including …
multistep endocytosis process and carry diverse functional molecular cargoes, including …
Engineered extracellular vesicles for cancer therapy
Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
Nanostructured particles assembled from natural building blocks for advanced therapies
Advanced treatments based on immune system manipulation, gene transcription and
regulation, specific organ and cell targeting, and/or photon energy conversion have …
regulation, specific organ and cell targeting, and/or photon energy conversion have …
Dendritic cell biology and its role in tumor immunotherapy
Y Wang, Y Xiang, VW Xin, XW Wang, XC Peng… - Journal of hematology & …, 2020 - Springer
As crucial antigen presenting cells, dendritic cells (DCs) play a vital role in tumor
immunotherapy. Taking into account the many recent advances in DC biology, we discuss …
immunotherapy. Taking into account the many recent advances in DC biology, we discuss …
Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment
S Wang, F Li, T Ye, J Wang, C Lyu, S Qing… - Science translational …, 2021 - science.org
Despite multiple immunotherapeutic technologies that achieve potent T cell activation,
effector T cells still lack efficiency because of the highly immunosuppressive conditions in …
effector T cells still lack efficiency because of the highly immunosuppressive conditions in …
Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source
W Meng, C He, Y Hao, L Wang, L Li, G Zhu - Drug delivery, 2020 - Taylor & Francis
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …
[HTML][HTML] Exosome-based vaccines: history, current state, and clinical trials
P Santos, F Almeida - Frontiers in immunology, 2021 - frontiersin.org
Extracellular vesicles (EVs) are released by most cell types as part of an intracellular
communication system in crucial processes such as inflammation, cell proliferation, and …
communication system in crucial processes such as inflammation, cell proliferation, and …