[HTML][HTML] Microglia, lifestyle stress, and neurodegeneration

C Madore, Z Yin, J Leibowitz, O Butovsky - Immunity, 2020 - cell.com
Recent years have witnessed a revolution in our understanding of microglia biology,
including their major role in the etiology and pathogenesis of neurodegenerative diseases …

[HTML][HTML] The links between the gut microbiome, aging, modern lifestyle and Alzheimer's disease

S Askarova, B Umbayev, AR Masoud… - Frontiers in cellular …, 2020 - frontiersin.org
Gut microbiome is a community of microorganisms in the gastrointestinal tract. These
bacteria have a tremendous impact on the human physiology in healthy individuals and …

Effects of physical activity and exercise interventions on Alzheimer's disease: an umbrella review of existing meta-analyses

S Lopez-Ortiz, S Lista, PL Valenzuela, J Pinto-Fraga… - Journal of …, 2023 - Springer
Introduction During the last decade, physical activity (PA)(or “exercise”) has been identified
as one of the main modifiable factors that influence the development of Alzheimer's disease …

The gut microbiome and Alzheimer's disease: Complex and bidirectional interactions

R Tarawneh, E Penhos - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Structural and functional alterations to the gut microbiome, referred to as gut dysbiosis, have
emerged as potential key mediators of neurodegeneration and Alzheimer disease (AD) …

[HTML][HTML] Exercise-induced myokines can explain the importance of physical activity in the elderly: an overview

JH Kwon, KM Moon, KW Min - Healthcare, 2020 - mdpi.com
Physical activity has been found to aid the maintenance of health in the elderly. Exercise-
induced skeletal muscle contractions lead to the production and secretion of many small …

[HTML][HTML] Physical exercise and Alzheimer's disease: effects on pathophysiological molecular pathways of the disease

S López-Ortiz, J Pinto-Fraga, PL Valenzuela… - International Journal of …, 2021 - mdpi.com
Alzheimer's disease (AD), the most common form of neurodegenerative dementia in adults
worldwide, is a multifactorial and heterogeneous disorder characterized by the interaction of …

[HTML][HTML] Relationships between mitochondrial dysfunction and neurotransmission failure in Alzheimer's disease

KY Wong, J Roy, ML Fung, BC Heng, C Zhang… - Aging and …, 2020 - ncbi.nlm.nih.gov
Besides extracellular deposition of amyloid beta and formation of phosphorylated tau in the
brains of patients with Alzheimer's disease (AD), the pathogenesis of AD is also thought to …

Exercise as a positive modulator of brain function

KA Alkadhi - Molecular neurobiology, 2018 - Springer
Various forms of exercise have been shown to prevent, restore, or ameliorate a variety of
brain disorders including dementias, Parkinson's disease, chronic stress, thyroid disorders …

[HTML][HTML] Exercise dosage in reducing the risk of dementia development: Mode, duration, and intensity—A narrative review

S Wang, HY Liu, YC Cheng, CH Su - International journal of …, 2021 - mdpi.com
Senile dementia, also known as dementia, is the mental deterioration which is associated
with aging. It is characterized by a decrease in cognitive abilities, inability to concentrate …

Psychobiotics for Mitigation of Neuro‐Degenerative Diseases: Recent Advancements

P Dhyani, C Goyal, SB Dhull… - Molecular nutrition & …, 2023 - Wiley Online Library
Ageing is inevitable and poses a universal challenge for all living organisms, including
humans. The human body experiences rapid cell division and metabolism until …