[HTML][HTML] Molecular mechanisms and clinical application of multipotent stem cells for spinal cord injury

M Szymoniuk, J Litak, L Sakwa, A Dryla, W Zezuliński… - Cells, 2022 - mdpi.com
Spinal Cord Injury (SCI) is a common neurological disorder with devastating psychical and
psychosocial sequelae. The majority of patients after SCI suffer from permanent disability …

[HTML][HTML] Microenvironment-targeted strategy steers advanced bone regeneration

S Hao, M Wang, Z Yin, Y Jing, L Bai, J Su - Materials Today Bio, 2023 - Elsevier
Abstract Treatment of large bone defects represents a great challenge in orthopedic and
craniomaxillofacial surgery. Traditional strategies in bone tissue engineering have focused …

Progress and emerging techniques for biomaterial-based derivation of mesenchymal stem cells (MSCs) from pluripotent stem cells (PSCs)

N Prakash, J Kim, J Jeon, S Kim, Y Arai… - Biomaterials …, 2023 - spj.science.org
The use of mesenchymal stem cells (MSCs) for clinical purposes has skyrocketed in the past
decade. Their multilineage differentiation potentials and immunomodulatory properties have …

[HTML][HTML] Mesenchymal stromal/stem cells and their extracellular vesicles in liver diseases: insights on their immunomodulatory roles and clinical applications

Q Huai, C Zhu, X Zhang, H Dai, X Li, H Wang - Cell & Bioscience, 2023 - Springer
Liver disease is a leading cause of mortality and morbidity that is rising globally. Liver
dysfunctions are classified into acute and chronic diseases. Various insults, including viral …

[HTML][HTML] Human macrophage migration inhibitory factor potentiates mesenchymal stromal cell efficacy in a clinically relevant model of allergic asthma

IJ Hawthorne, H Dunbar, C Tunstead, T Schorpp… - Molecular Therapy, 2023 - cell.com
Current asthma therapies focus on reducing symptoms but fail to restore existing structural
damage. Mesenchymal stromal cell (MSC) administration can ameliorate airway …

[HTML][HTML] Umbilical cord-derived mesenchymal stem cell sheets transplanted subcutaneously enhance cell retention and survival more than dissociated stem cell …

M Nakao, M Matsui, K Kim, N Nishiyama… - Stem Cell Research & …, 2023 - Springer
Background Human umbilical cord-derived mesenchymal stem cell (hUC-MSC) sheets have
recently attracted attention as an alternative approach to injected cell suspensions for stem …

[HTML][HTML] Mesenchymal stem cell-derived exosomes as delivery vehicles for non-coding RNAs in lung diseases

Y Feng, K Guo, J Jiang, S Lin - Biomedicine & Pharmacotherapy, 2024 - Elsevier
The burden of lung diseases is gradually increasing with an increase in the average human
life expectancy. Therefore, it is necessary to identify effective methods to treat lung diseases …

[HTML][HTML] Exosomes derived from mesenchymal stem cells primed with disease-condition-serum improved therapeutic efficacy in a mouse rheumatoid arthritis model …

EW Choi, IR Lim, JH Park, J Song, B Choi… - Stem Cell Research & …, 2023 - Springer
Backgrounds Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease
characterized by synovial inflammation-mediated progressive destruction of the cartilage …

[HTML][HTML] Mesenchymal stem cells in the treatment of spinal cord injury: Mechanisms, current advances and future challenges

Y Xia, J Zhu, R Yang, H Wang, Y Li, C Fu - Frontiers in Immunology, 2023 - frontiersin.org
Spinal cord injury (SCI) has considerable impact on patient physical, mental, and financial
health. Secondary SCI is associated with inflammation, vascular destruction, and …

[HTML][HTML] Mesenchymal Stem Cell (MSC)-Based Drug Delivery into the Brain across the Blood–Brain Barrier

T Tashima - Pharmaceutics, 2024 - mdpi.com
At present, stem cell-based therapies using induced pluripotent stem cells (iPSCs) or
mesenchymal stem cells (MSCs) are being used to explore the potential for regenerative …