[PDF][PDF] Growth hormone deficiency and NAFLD: An overlooked and underrecognized link

I Doycheva, D Erickson, KD Watt - Hepatology Communications, 2022 - Wiley Online Library
Growth hormone and its mediator insulin‐like growth factor‐1 exert their effect on different
organs and control various physiologic metabolic processes. Adult growth hormone …

Towards understanding the direct and indirect actions of growth hormone in controlling hepatocyte carbohydrate and lipid metabolism

MC Vázquez-Borrego, M del Rio-Moreno, RD Kineman - Cells, 2021 - mdpi.com
Growth hormone (GH) is critical for achieving normal structural growth. In addition, GH plays
an important role in regulating metabolic function. GH acts through its GH receptor (GHR) to …

Central regulation of metabolism by growth hormone

J Donato Jr, F Wasinski, IC Furigo, M Metzger… - Cells, 2021 - mdpi.com
Growth hormone (GH) is secreted by the pituitary gland, and in addition to its classical
functions of regulating height, protein synthesis, tissue growth, and cell proliferation, GH …

New findings on brain actions of growth hormone and potential clinical implications

J Donato Jr, JJ Kopchick - Reviews in Endocrine and Metabolic Disorders, 2023 - Springer
Growth hormone (GH) is secreted by somatotropic cells of the anterior pituitary gland. The
classical effects of GH comprise the stimulation of cell proliferation, tissue and body growth …

[HTML][HTML] Pharmaco-epi-genetic and patho-physiology of gestational diabetes mellitus (GDM): An overview

A Shamsad, AS Kushwah, R Singh, M Banerjee - Health Sciences Review, 2023 - Elsevier
Gestational diabetes mellitus (GDM) is a medical complication of glycaemic intolerance that
develops in 2 nd or 3 rd trimester of pregnancy. The speculative cause behind insulin …

Predictors of response to anamorelin in gastrointestinal cancer patients with cachexia: a retrospective study

N Iwai, H Sakai, K Oka, J Sakagami, T Okuda… - Supportive Care in …, 2023 - Springer
Purpose Anamorelin, a ghrelin receptor agonist, has recently been approved for gastric,
pancreatic, and colorectal cancer patients with cachexia in Japan. However, only few …

Human CIDEC transgene improves lipid metabolism and protects against high-fat diet–induced glucose intolerance in mice

A Gupta, B Balakrishnan, S Karki, M Slayton… - Journal of Biological …, 2022 - ASBMB
Cell death–inducing DNA fragmentation factor-like effector C (CIDEC) expression in adipose
tissue positively correlates with insulin sensitivity in obese humans. Further, E186X, a single …

Changes of Signaling Pathways in Hypothalamic Neurons with Aging

PM Masliukov - Current Issues in Molecular Biology, 2023 - mdpi.com
The hypothalamus is an important regulator of autonomic and endocrine functions also
involved in aging regulation. The aging process in the hypothalamus is accompanied by …

Acromegaly: Overview and associated temporomandibular joint disorders

M Al‐Hadlaq, H Sroussi - Oral Diseases, 2024 - Wiley Online Library
Objective To provide a review on acromegaly and its orofacial manifestations, with a focus
on associated arthropathies and temporomandibular joint disorders (TMD). Methods A …

Adverse metabolic effects on glucose in patients receiving anamorelin using a Japanese claims database

H Ohta, T Horii, T Yasu - Oncology, 2023 - karger.com
Background: Anamorelin is the first drug approved for the treatment of cancer cachexia, a
debilitating condition characterized by weight loss, anorexia, and muscle mass depletion …