Several podophyllotoxin derivatives modified in the A, B, C, D and E rings were prepared
from podophyllotoxin and methyl isoxazopodophyllic acid and evaluated for their cytotoxicity …

Objective: The aim of the present review is to give an overview about the role, biosynthesis,
and characteristics of Podophyllotoxin (PTOX) as a potential antitumor agent with particular …

Human papillomavirus (HPV) is a significant source of morbidity and mortality worldwide.
The primary risk factors for acquiring HPV are generally associated with sexual activity …

The aryltetralin-type lignan podophyllotoxin, the main agent present in the resin extracted
from the rhizomes of different podophyllum species, possesses important antineoplastic and …

Objective: This study examined the incidence of and healthcare costs attributable to genital
warts within a large US commercially insured, geographically dispersed population …

Context: Podophyllotoxin, a pharmaceutically important bioactive compound of Podophyllum
sps.(Berberidaceae), is in great demand worldwide as an anticancer and antivirus drug …

The relatively high recurrence rate of genital warts can be attributed to the unsuccessful
elimination of viruses in areas of subclinical and latent infection. Therefore, the identification …

We describe a prospective study designed to assess the effectiveness of the commonly used
clinic-based treatments for genital warts individually and in combination. Patients presenting …

Genital warts are a cosmetic nuisance. They are caused by low-risk human papillomavirus
types, have no oncogenic potential and are not linked to cervical cancer. However, they …

External anogenital warts, or condylomata acuminata, are caused by the proliferation of
squamous epithelial cells secondary to human papillomavirus infection. In sexually active …