[HTML][HTML] Proactive and reactive roles of TGF-β in EMT-induced plasticity

NA Kuburich, T Sabapathy, BR Demestichas… - Seminars in cancer …, 2023 - Elsevier
Cancer cells adapt to varying stress conditions to survive through plasticity. Stem cells
exhibit a high degree of plasticity, allowing them to generate more stem cells or differentiate …

[HTML][HTML] Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms

B Brown, V Ojha, I Fricke, SA Al-Sheboul, C Imarogbe… - Vaccines, 2023 - mdpi.com
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Unique role of vimentin networks in compression stiffening of cells and protection of nuclei from compressive stress

K Pogoda, F Byfield, P Deptuła, M Cieśluk… - Nano Letters, 2022 - ACS Publications
In this work, we investigate whether stiffening in compression is a feature of single cells and
whether the intracellular polymer networks that comprise the cytoskeleton (all of which stiffen …

Signaling pathways and protein–protein interaction of vimentin in invasive and migration cells: A review

DH Karoii, H Azizi, M Amirian - Cellular reprogramming, 2022 - liebertpub.com
The vimentin (encoded by VIM) is one of the 70 human intermediate filaments (IFs), building
highly dynamic and cell-type-specific web networks in the cytoplasm. Vim−/− mice exhibit …

[HTML][HTML] The Role of RKIP in the Regulation of EMT in the Tumor Microenvironment

H Cessna, S Baritaki, A Zaravinos, B Bonavida - Cancers, 2022 - mdpi.com
Simple Summary Raf kinase inhibitor protein (RKIP) expression in cancer cells is
significantly reduced and promoting cancer cells growth and invasiveness. Overexpresssion …

A review of protein-protein interaction and signaling pathway of Vimentin in cell regulation, morphology and cell differentiation in normal cells

D Hashemi Karoii, H Azizi - Journal of Receptors and Signal …, 2022 - Taylor & Francis
The Vimentin intermediate filament (VIF) is an essential cytoskeleton component. It shows
dynamically changing expression patterns throughout various phases of the differentiation …

[HTML][HTML] Relationship between epithelial-to-mesenchymal transition and tumor-associated macrophages in colorectal liver metastases

A Gazzillo, MA Polidoro, C Soldani… - International Journal of …, 2022 - mdpi.com
The liver is the most common metastatic site in colorectal cancer (CRC) patients. Indeed, 25–
30% of the cases develop colorectal liver metastasis (CLM), showing an extremely poor 5 …

[HTML][HTML] Citrullinated and malondialdehyde-acetaldehyde modified fibrinogen activates macrophages and promotes an aggressive synovial fibroblast phenotype in …

N Aripova, MJ Duryee, BR England, CD Hunter… - Frontiers in …, 2023 - frontiersin.org
Objective Post-translational protein modifications with malondialdehyde-acetaldehyde
(MAA) and citrulline (CIT) are implicated in the pathogenesis of rheumatoid arthritis (RA) …

[HTML][HTML] Extracellular vimentin is sufficient to promote cell attachment, spreading, and motility by a mechanism involving N-acetyl glucosamine-containing structures

R Bucki, DV Iwamoto, X Shi, KE Kerr, FJ Byfield… - Journal of Biological …, 2023 - ASBMB
Vimentin intermediate filaments form part of the cytoskeleton of mesenchymal cells, but
under pathological conditions often associated with inflammation, vimentin filaments …

[HTML][HTML] Effects of Periplaneta americana extracts on the growth and proliferation of cutaneous interstitial cells in cutaneous-wound healing

Z Liang, G Han, Z Luo, B Li, W Liu… - Frontiers in pharmacology, 2022 - frontiersin.org
Cutaneous-wound healing requires a coordinated reaction of multiple cells, including
interstitial cells. Impaired recovery of cutaneous wounds can lead to various adverse health …