Highly signal-responsive gene regulatory network governing Myxococcus development

L Kroos - Trends in genetics, 2017 - cell.com
The bacterium Myxococcus xanthus undergoes multicellular development when starved.
Thousands of cells build mounds in which some differentiate into spores. This remarkable …

Myxobacteria, polarity, and multicellular morphogenesis

D Kaiser, M Robinson, L Kroos - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
Myxobacteria are renowned for the ability to sporulate within fruiting bodies whose shapes
are species-specific. The capacity to build those multicellular structures arises from the …

Regulated proteolysis in bacterial development

A Konovalova, L Søgaard-Andersen… - FEMS microbiology …, 2014 - academic.oup.com
Bacteria use proteases to control three types of events temporally and spatially during the
processes of morphological development. These events are the destruction of regulatory …

Molecular mechanisms of signaling in Myxococcus xanthus development

DJ Bretl, JR Kirby - Journal of molecular biology, 2016 - Elsevier
Myxococcus xanthus is an environmental bacterium that displays a complex life cycle that
includes motility, predation, multicellular fruiting body development, and sporulation. Given …

To∼ P or Not to∼ P? Non‐canonical activation by two‐component response regulators

SK Desai, LJ Kenney - Molecular Microbiology, 2017 - Wiley Online Library
Bacteria sense and respond to their environment through the use of two‐component
regulatory systems. The ability to adapt to a wide range of environmental stresses is directly …

Myxococcus xanthus developmental cell fate production: heterogeneous accumulation of developmental regulatory proteins and reexamination of the role of MazF in …

B Lee, C Holkenbrink, A Treuner-Lange… - Journal of …, 2012 - Am Soc Microbiol
Myxococcus xanthus undergoes a starvation-induced multicellular developmental program
during which cells partition into three known fates:(i) aggregation into fruiting bodies …

Global transcriptome analysis of spore formation in Myxococcus xanthus reveals a locus necessary for cell differentiation

FD Müller, A Treuner-Lange, J Heider, SM Huntley… - BMC genomics, 2010 - Springer
Background Myxococcus xanthus is a Gram negative bacterium that can differentiate into
metabolically quiescent, environmentally resistant spores. Little is known about the …

Working together for the common good: cell-cell communication in bacteria

AM Stevens, M Schuster, KP Rumbaugh - Journal of bacteriology, 2012 - Am Soc Microbiol
The 4th ASM Conference on Cell-Cell Communication in Bacteria was held in Miami, FL,
from 6 to 9 November 2011. This review highlights three key themes that emerged from the …

A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection

SA Shelburne, RJ Olsen, B Suber… - PLoS …, 2010 - journals.plos.org
Transcriptional regulatory networks are fundamental to how microbes alter gene expression
in response to environmental stimuli, thereby playing a critical role in bacterial …

Enhancer binding proteins act as hetero-oligomers and link secondary metabolite production to myxococcal development, motility, and predation

C Volz, C Kegler, R Müller - Chemistry & biology, 2012 - cell.com
Motile predatory Myxobacteria are producers of multiple secondary metabolites and, on
starvation, undergo concerted cellular differentiation to form multicellular fruiting bodies …