[HTML][HTML] Hepatic metastasis from colorectal cancer

AWC Kow - Journal of gastrointestinal oncology, 2019 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most common cancers in the world. About two third of
patients with CRC will develop distant recurrence at some point in time. Liver is the most …

Survival advantage of laparoscopic versus open resection for colorectal liver metastases: a meta-analysis of individual patient data from randomized trials and …

NL Syn, T Kabir, YX Koh, HL Tan, LZ Wang… - Annals of …, 2020 - journals.lww.com
Objective: To perform an individual participant data meta-analysis using randomized trials
and propensity-score matched (PSM) studies which compared laparoscopic versus open …

Resection margin and survival in 2368 patients undergoing hepatic resection for metastatic colorectal cancer: surgical technique or biologic surrogate?

E Sadot, BG Koerkamp, JN Leal, J Shia… - Annals of …, 2015 - journals.lww.com
Objectives: The impact of margin width on overall survival (OS) in the context of other
prognostic factors after resection for colorectal liver metastases is unclear. We evaluated the …

First long-term oncologic results of the ALPPS procedure in a large cohort of patients with colorectal liver metastases

H Petrowsky, M Linecker, DA Raptis… - Annals of …, 2020 - journals.lww.com
Objectives: To analyze long-term oncological outcome along with prognostic risk factors in a
large cohort of patients with colorectal liver metastases (CRLM) undergoing ALPPS …

Impact of surgical margin width on recurrence and overall survival following R0 hepatic resection of colorectal metastases: a systematic review and meta-analysis

GA Margonis, TN Sergentanis… - Annals of …, 2018 - journals.lww.com
Objective: To examine the impact of surgical margin width on survival following R0 hepatic
resection for colorectal metastases (CRLM). Summary of Background Data: Although …

RAS Mutation Predicts Positive Resection Margins and Narrower Resection Margins in Patients Undergoing Resection of Colorectal Liver Metastases

KW Brudvik, Y Mise, MH Chung, YS Chun… - Annals of surgical …, 2016 - Springer
Background In patients undergoing resection of colorectal liver metastases (CLM), resection
margin status is a significant predictor of survival, particularly in patients with suboptimal …

Impact of postoperative complications on survival and recurrence after resection of colorectal liver metastases: systematic review and meta-analysis

D Dorcaratto, G Mazzinari, M Fernandez… - Annals of …, 2019 - journals.lww.com
Objective: To study the effect of postoperative complications (POC) on overall survival (OS)
and disease-free survival (DFS) after surgical resection of colorectal liver metastases …

[HTML][HTML] Adjuvant chemotherapy for resected colorectal cancer metastases: Literature review and meta-analysis

G Brandi, S De Lorenzo, M Nannini, S Curti… - World journal of …, 2016 - ncbi.nlm.nih.gov
Surgical resection is the only option of cure for patients with metastatic colorectal cancer
(CRC). However, the risk of recurrence within 18 mo after metastasectomy is around 75 …

KRAS Mutation Status Dictates Optimal Surgical Margin Width in Patients Undergoing Resection of Colorectal Liver Metastases

GA Margonis, K Sasaki, N Andreatos, Y Kim… - Annals of surgical …, 2017 - Springer
Background The optimal tumor-free margin width remains controversial and may be
inappropriate to investigate without considering differences in the underlying tumor biology …

R1 resection for colorectal liver metastases: a survey questioning surgeons about its incidence, clinical impact, and management

L Viganò, G Costa, MM Cimino, F Procopio… - Journal of …, 2018 - Elsevier
Background A≥ 1-mm margin is standard for resection of colorectal liver metastases (CLM).
However, R1 resection is not rare (10–30%), and chemotherapy could mitigate its impact …