Specific interactions between proteins and DNA are fundamental to many biological
processes. In this review, we provide a revised view of protein-DNA interactions that …

Genome architecture has proven to be critical in determining gene regulation across almost
all domains of life. While many of the key components and mechanisms of eukaryotic …

The micF gene is a stress response gene found in Escherichia coli and related bacteria that
post-transcriptionally controls expression of the outer membrane porin gene ompF. The micF …

We have used nylon membranes spotted in duplicate with full-length polymerase chain
reaction-generated products of each of the 4,290 predicted Escherichia coli K12 open …

The importance of regulatory control in metabolic processes is widely acknowledged, and
several enquiries (both local and global) are being made in understanding regulation at …

Pre‐replication complexes (pre‐RC) assemble on replication origins and unwind DNA in the
presence of chromatin proteins. As components of Escherichia coli pre‐RC, two histone‐like …

Genome duplication is a critical event in the reproduction cycle of every cell. Because all
daughter cells must inherit a complete genome, chromosome replication is tightly regulated …

Triggering new rounds of chromosomal DNA replication during the bacterial cell cycle is
exquisitely regulated, ensuring both proper timing and one round per cycle stringency. A …

Bacterial pathogenic growth requires a swift coordination of pathogenicity function with
various kinds of environmental stress encountered in the course of host infection. Among the …

The cell–cell signaling process called quorum sensing allows bacteria to control behaviors
in response to changes in population density. In Vibrio harveyi, the master quorum‐sensing …